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2015 年度 実施状況報告書

Learning to control brain activity pattern using real-time functional MRI: A feasibility study

研究課題

研究課題/領域番号 26350993
研究機関名古屋大学

研究代表者

Bagarinao E.  名古屋大学, 脳とこころの研究センター, 特任准教授 (00443218)

研究期間 (年度) 2014-04-01 – 2017-03-31
キーワードreal-time functional MRI / neurofeedback / support vector machine / brain machine interface / machine learning
研究実績の概要

Overall, the research went as plan. The second year of the project was devoted to performing the actual experiments in which participants were trained to control their brain activity pattern using real-time functional MRI neurofeedback. To this end, a support vector machine (SVM) was used to classify on-going brain activation patterns. A correct match of the participant's brain activity to the target pattern would move a displayed arrow to the right (representing the feedback signal). Thus, the better the participant was in reproducing the correct activation pattern, the further the arrow would move.

Before the end of the last academic year (AY2015), 30 participants were recruited and scanned. Initial analysis of the acquired datasets from 17 participants was also carried out. The initial results showed that trained SVMs attained classification accuracy greater than 90% using data from the training scans. On the other hand, real-time classification performance during feedback scans varied depending on the task used: 81% for imagined finger tapping task, 88% for word generation task, and 85% for serial subtraction task. Overall, this high classification accuracy enabled participants to successfully control the movement of the arrow used as feedback in the study.

Finally, the results of the initial analysis were presented in domestic as well as international conferences.

現在までの達成度 (区分)
現在までの達成度 (区分)

2: おおむね順調に進展している

理由

The second year of the project progressed rather smoothly. We were able to recruit and scanned 30 participants in total, more than the initial target. This is in spite of the center's MRI scanner problem happening at the latter part of 2015. The result of the initial analysis was also very promising. Classification accuracy of the trained SVM was quite high (more than 80%) suggesting the feasibility of the used method.

今後の研究の推進方策

For this academic year (AY2016), additional scans will be conducted with a minimum target of 3 more participants. After all the scans are performed, analysis of the full dataset will be undertaken. The results of the analysis will be presented in upcoming domestic and international conferences. The main findings will also be compiled into a manuscript and will be submitted to some journals for possible publication.

次年度使用額が生じた理由

Most of the scans went smoothly that instead of the allotted 3-hour scan per session, the scans usually finished within two hours or less. This gave us more scan time for additional participants. Unfortunately, some participants were not scanned last academic year due to the problem with the Brain and Mind Research Center's MRI scanner in the latter part of 2015. The scanner's gradient coil needed to be replaced. There was also some delay in the recruitment of the project's research assistant. Because of these factors, not all of the fund were disbursed completely during the academic year.

次年度使用額の使用計画

The remaining amount will be used to cover the expenses for the scanning of additional participants. It will also be used for the dissemination of the research output such as presentation in domestic conferences as well as publication expenses.

  • 研究成果

    (3件)

すべて 2015

すべて 学会発表 (3件) (うち国際学会 2件)

  • [学会発表] Detecting activation patterns from functional MRI datasets with undetermined event onsets using support vector machines2015

    • 著者名/発表者名
      E. Bagarinao, S. Maesawa, H. Watanabe, H. Isoda
    • 学会等名
      45th Annual Meeting of the Society for Neuroscience (Neuroscience 2015)
    • 発表場所
      Chicago, IL, USA
    • 年月日
      2015-10-17 – 2015-10-21
    • 国際学会
  • [学会発表] Applications of support vector machines in neuroimaging studies: Identifying imaging biomarkers and real-time brain state decoding2015

    • 著者名/発表者名
      E. Bagarinao
    • 学会等名
      BrainConnects 2015
    • 発表場所
      Nagoya, Aichi, Japan
    • 年月日
      2015-07-31 – 2015-08-01
    • 国際学会
  • [学会発表] Real-time classification of brain activation patterns using support vector machine and its potential application as a tool for cognitive training2015

    • 著者名/発表者名
      E. Bagarinao, S. Maesawa, H. Watanabe, D. Mori, T. Nakai, H. Isoda, and G. Sobue
    • 学会等名
      38th Annual Meeting of the Japan Neuroscience Society
    • 発表場所
      Kobe, Japan
    • 年月日
      2015-07-28 – 2015-07-31

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公開日: 2017-01-06  

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