| 研究実績の概要 |
Purpose: To clarify differences between highly myopic and non-myopic primary open-angle glaucoma (POAG) patients, including normal-tension glaucoma patients.
Methods: A total of 269 POAG patients were divided into two groups: patients with ≥26.5 mm of axial length (highly myopic group) and patients with <24.0 mm of axial length (non-myopic group).
Results: We analyzed 53 highly myopic and 93 non-myopic POAG patients.According to the mean deviation definition of progression, the cumulative probability of non-progression of visual field (VF) loss was significantly greater in the highly myopic group (10-year survival rate, 73.7±6.8%) than in the non-myopic group (10-year survival rate, 46.3±5.8%; log-rank test, P=0.0142). The occurrence of disc hemorrhage (DH) of the non-myopic group (1.60±3.04) was significantly greater than the highly myopic group (0.93±2.13; P=0.0311). The cumulative probability of DH was significantly greater in the non-myopic group (10-year survival rate, 47.2±6.6%) than in the highly myopic group (10-year survival rate, 26.4±5.4%; log-rank test, P=0.0413).
Conclusions: Highly myopic POAG is considered a combination of myopic optic neuropathy and glaucomatous optic neuropathy (GON). If GON is predominant, it has frequent DH and more progressive VF loss. However, when the GON is predominant, it has less DH, and less progressive VF loss.
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