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Neural activity related to construction of compound images in the macaque prefrontal cortex

Research Project

Project/Area Number 20500355
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Neurophysiology and muscle physiology
Research InstitutionNiigata University

Principal Investigator

HASEGAWA Isao  Niigata University, 医歯学系, 教授 (60282620)

Co-Investigator(Kenkyū-buntansha) TODA Haruo  新潟大学, 医歯学系, 講師 (10217507)
IIJIMA Atsuhiko  新潟大学, 自然科学系, 助教 (00377186)
KAWASAKI Keisuke  新潟大学, 医歯学系, 助教 (60511178)
Project Period (FY) 2008 – 2010
Project Status Completed (Fiscal Year 2010)
Budget Amount *help
¥4,680,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥1,080,000)
Fiscal Year 2010: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2009: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2008: ¥3,380,000 (Direct Cost: ¥2,600,000、Indirect Cost: ¥780,000)
Keywords認知 / 記憶 / マカクザル / 前頭葉 / 電気生理 / 視覚 / 図形 / 大脳
Research Abstract

Japanese monkeys were trained in a symbolic construction matching-to-sample (SCMS) task in which 6 compound figures symbolically represent 6 objects. Behavioral experiments showed that the monkeys could learn the SCMS task, and generalize from item-object associations to category-object associations. We developed ultra-thin flexible electrode arrays for electrocorticogram (ECoG), and implanted them into the prefrontal cortex of the monkeys. During the SCMS task, ECoG responses to the second sample element was induced earlier and became larger than during sample presentation of a compound figure in a symbolic matching-to-sample task.

Report

(4 results)
  • 2010 Annual Research Report   Final Research Report ( PDF )
  • 2009 Annual Research Report
  • 2008 Annual Research Report
  • Research Products

    (47 results)

All 2011 2010 2009 2008 Other

All Journal Article (13 results) (of which Peer Reviewed: 10 results) Presentation (27 results) Book (2 results) Patent(Industrial Property Rights) (5 results)

  • [Journal Article] Simultaneous recording of ECoG and intracortical neuronal activity using a flexible multichannel electrode-mesh in visual cortex2011

    • Author(s)
      Toda H, Suzuki T, Sawahata H, Majima K, Kamitani Y, Hasegawa I
    • Journal Title

      Neuroimage 54

      Pages: 203-212

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Simultaneous recording of ECoG and intracortical neuronal activity using a flexible multichannel electrode-mesh in visual cortex.2011

    • Author(s)
      Toda H, Suzuki T, Sawahata H, Majima K, Kamitani Y, Hasegawa I.
    • Journal Title

      Neuroimage

      Volume: 54 Pages: 203-212

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 前脳のGABA受容体による自律機能の調節2010

    • Author(s)
      山口賢一、山田貴穗、濱齊、渡辺賢一、長谷川功
    • Journal Title

      新潟医学会雑誌 (In press)

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article]2010

    • Author(s)
      長谷川功(編集:伊藤正男・川合述史)
    • Journal Title

      ブレインサイエンス・レビュー2010(プレインサイエンス振興財団株式会社クバプロ)

      Pages: 209-222

    • Related Report
      2009 Annual Research Report
  • [Journal Article] 前脳GABA(A)受容体とバゾプレッシン分泌2009

    • Author(s)
      山口賢一、山田貴穂、長谷川功
    • Journal Title

      生体の科学 60

      Pages: 378-379

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] 前脳GABA(A)受容体とバゾプレッシン分泌2009

    • Author(s)
      山口賢一、山田貴穗、長谷川功
    • Journal Title

      生体の科学60 5

      Pages: 378-379

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 記憶を貯める脳、活かす脳2008

    • Author(s)
      長谷川功
    • Journal Title

      新潟医学会雑誌 122

      Pages: 663-668

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] 認知記憶の脳内表現とその活性化2008

    • Author(s)
      長谷川功、飯島淳彦、戸田春男
    • Journal Title

      新潟県医師会報 696

      Pages: 1-5

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] 記憶を貯める脳、活かす脳2008

    • Author(s)
      長谷川 功
    • Journal Title

      新潟医学会雑誌 122

      Pages: 663-668

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 認知記憶の脳内表現とその活性化2008

    • Author(s)
      長谷川功, 飯島淳彦, 戸田春男
    • Journal Title

      新潟県医師会報 696

      Pages: 1-5

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Intrasulcal electrocorticography in macaque monkeys with minimally invasive neurosurgical protocols.

    • Author(s)
      Matsuo T, Kawasaki K, Osada T, Sawahata H, Suzuki T, Shibata M, Miyakawa N, Nakahara K, Iijima A,, Sato N, Kawai K, Saito N, Hasegawa I
    • Journal Title

      Frontiers in Systems Neuroscience in press

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] 前脳のGABA 受容体による自律機能の調節

    • Author(s)
      山口賢一、山田貴穂、濱齊、渡辺賢一、長谷川功
    • Journal Title

      新潟医学会雑誌 in press

    • Related Report
      2010 Final Research Report
  • [Journal Article] 前脳のGABA受容体による自律機能の調節

    • Author(s)
      山口賢一、山田貴穂、濱齊、渡辺賢一、長谷川功
    • Journal Title

      新潟医学会雑誌

      Volume: In press

    • Related Report
      2010 Annual Research Report
  • [Presentation] Symmetry and generalization in visual-visual association learning in macaque monkeys2010

    • Author(s)
      Iijima A, Kawasaki K, Hatano Y, Fujisawa N, Hasegawa I.
    • Organizer
      Soc Neurosci Abstr 36
    • Place of Presentation
      San Diego USA(in press)
    • Year and Date
      2010-11-17
    • Related Report
      2010 Final Research Report
  • [Presentation] Symmetry and generalization in visual visual association learning in macaque monkeys2010

    • Author(s)
      Iijima A, Kawasaki K, Hatano Y Fujisawa N, Hasegawa I
    • Organizer
      Society for Neuroscience 2010
    • Place of Presentation
      San Diego USA
    • Year and Date
      2010-11-17
    • Related Report
      2010 Annual Research Report
  • [Presentation] Electrocorticography within the superior temporal sulcus of macaques2010

    • Author(s)
      Matsuo T, Kawasaki K, Sawahata H, Shibata M, Miyakawa N, Kawai K, Satou N, Saito N, Nakahara K,Suzuki T, Hasegawa I.
    • Organizer
      Soc Neurosci Abstr 36,123,
    • Place of Presentation
      San Diego USA
    • Year and Date
      2010-11-16
    • Related Report
      2010 Final Research Report
  • [Presentation] Electrocorticography within the superior temporal sulcus of macaques2010

    • Author(s)
      Matsuo T, Kawasaki K, Sawahato H, Shibata M, Miyakawa N, Kawai K, Satou N, Saito N, Nakahara K, Suzuki T, Hasegawa I.
    • Organizer
      Society for Neuroscience 2010
    • Place of Presentation
      San Diego USA
    • Year and Date
      2010-11-16
    • Related Report
      2010 Annual Research Report
  • [Presentation] Neural decoding of visual object categories using temporal patterns of ECoG signals2010

    • Author(s)
      Majima K, Matsuo T, KawasakiK, Kawai K, Masuda H, KuniiN, Murakami H, Kamada K, Kameyama S, Saito N, HasegawaI, Kamitani Y
    • Organizer
      Society for Neuroscience 2010
    • Place of Presentation
      San Diego USA
    • Year and Date
      2010-11-16
    • Related Report
      2010 Annual Research Report
  • [Presentation] Improvement of a flexible Parylene ECoG electrode for long-term stable recording2010

    • Author(s)
      Suzuki T, Kotake N, FukayamaO, Takeuchi S, Watanabe H, IsaT, Sawahata H, Toda H, Hasegawa I, Mabuchi K.
    • Organizer
      Society for Neuroscience 2010
    • Place of Presentation
      San Diego USA
    • Year and Date
      2010-11-13
    • Related Report
      2010 Annual Research Report
  • [Presentation] 視覚刺激に対する瞳孔径・瞳孔反応とストレス評価2010

    • Author(s)
      飯島淳彦、小杉剛、木竜徹、長谷川功、板東武彦
    • Organizer
      第25回生体・生理工学シンポジウム
    • Place of Presentation
      岡山
    • Year and Date
      2010-09-23
    • Related Report
      2010 Annual Research Report
  • [Presentation] Neural decoding of visual oblect categories using temporal pattems of ECoG signals2010

    • Author(s)
      Majima K, Matsuo T, Kawasaki K, Kawai K, Masuda H, KuniiN, Murakami H, Kamada K, Kameyama S, Saito N, HasegawaI, Kamitani Y.
    • Organizer
      第33回日本神経科学大会
    • Place of Presentation
      神戸
    • Year and Date
      2010-09-04
    • Related Report
      2010 Annual Research Report
  • [Presentation] An evaluation of recording qualities of MEMS-based mesh ECoG electrode2010

    • Author(s)
      Sawahata H, Suzuki T, KotakeN, Majima K, Kamitani Y, TodaH, Hasegawa I
    • Organizer
      第33回日本神経科学大会
    • Place of Presentation
      神戸
    • Year and Date
      2010-09-03
    • Related Report
      2010 Annual Research Report
  • [Presentation] Electrocorticographic mapping of human ventral visual areas2010

    • Author(s)
      Matsuo T, Kawasaki T, Kawai K, Masuda H, Kunii N, Murakami H, Majima K, Kamada K, Kamitani Y, Kameyama K, SaitoN, Hasegawa I.
    • Organizer
      第33回日本神経科学大会
    • Place of Presentation
      神戸
    • Year and Date
      2010-09-03
    • Related Report
      2010 Annual Research Report
  • [Presentation] Regression of forearm reach and grasp movement trajectories using intracortical local field2010

    • Author(s)
      Watanabe H, Sakatani T, Togawa T, Yoshida M, Toda H, Sawahata H, Isa T, Hasegawa I, Suzuki T, Yamashita M, Sato M, Kawato M.
    • Organizer
      第33回日本神経科学大会
    • Place of Presentation
      神戸
    • Year and Date
      2010-09-03
    • Related Report
      2010 Annual Research Report
  • [Presentation] Symbolization of object categories by macaque monkeys2010

    • Author(s)
      Iijima A, Hatano Y, Fujisawa N, Hasegawa I.
    • Organizer
      Neurosci Res 68 suppl,e180,2010
    • Place of Presentation
      神戸
    • Year and Date
      2010-09-02
    • Related Report
      2010 Final Research Report
  • [Presentation] Symbolization of object categories by macaque monkeys2010

    • Author(s)
      Iijima A, Hatano Y, Fujisawa N, Hasegawa I.
    • Organizer
      第33回日本神経科学大会
    • Place of Presentation
      神戸
    • Year and Date
      2010-09-02
    • Related Report
      2010 Annual Research Report
  • [Presentation] Gene transfer into the primate central nervous system via antero-and retrograde infections by adeno-associated viruses2010

    • Author(s)
      Masamizu Y, Okada N, Kawasaki K, Ishibashi H, Takeda S, Yuasa S, Hasegawa I, Nakahara K.
    • Organizer
      第33回日本神経科学大会
    • Place of Presentation
      神戸
    • Year and Date
      2010-09-02
    • Related Report
      2010 Annual Research Report
  • [Presentation] The basis of the EcoG signal in visual cortex2010

    • Author(s)
      Hasegawa I
    • Organizer
      2nd UK-Japan Workshop on the Brain-Machine Interface
    • Place of Presentation
      Newcastle, UK
    • Year and Date
      2010-02-26
    • Related Report
      2010 Final Research Report
  • [Presentation] The basis of the EcoG signal in visual cortex2010

    • Author(s)
      Hasegawa I.
    • Organizer
      2^<nd> UK-Japan Workshop on the Brain-Machine Interface
    • Place of Presentation
      Newcastle, UK
    • Year and Date
      2010-02-26
    • Related Report
      2009 Annual Research Report
  • [Presentation] Simultaneous recording of high density electrocorticogram and intracortical activity using MEMS-fabricated electrode array2010

    • Author(s)
      Toda H, Sawahata H, Suzuki T, Majilna K, Kamitani Y, HasegawaI.
    • Organizer
      第87回日本生理学会大会
    • Place of Presentation
      盛岡
    • Related Report
      2010 Annual Research Report
  • [Presentation] Simultaneous recording of visual cortical response by a meshelectrode array and an intracortical microelectrode2009

    • Author(s)
      Toda H, Sawahata H, Suzuki T, Watanabe H, Isa T, Hasegawa I.
    • Organizer
      Society for Neuroscience Abstr
    • Place of Presentation
      Chicago, USA
    • Year and Date
      2009-10-21
    • Related Report
      2009 Annual Research Report
  • [Presentation] 映像の動き成分が脳血流に与える影響2009

    • Author(s)
      飯島淳彦, 鵜飼一彦, 木竜徹, 長谷川功, 板東武彦
    • Organizer
      第24回生体生理工学シンポジウム
    • Place of Presentation
      仙台
    • Year and Date
      2009-09-26
    • Related Report
      2009 Annual Research Report
  • [Presentation] Mesh electrode arrays applied to record visual cortical activities in hooded rats2009

    • Author(s)
      Sawahata H, Toda H., Suzuki T., Hasegawa I.
    • Organizer
      Neurosci Res第32回日本神経科学大会
    • Place of Presentation
      名古屋
    • Year and Date
      2009-09-17
    • Related Report
      2009 Annual Research Report
  • [Presentation] 大脳視覚イメージの活性化と解読2009

    • Author(s)
      長谷川功
    • Organizer
      第29回関東機能的脳外科カンファレンス
    • Place of Presentation
      東京
    • Year and Date
      2009-09-05
    • Related Report
      2009 Annual Research Report
  • [Presentation] イメージを浮かべる脳、覚える脳2009

    • Author(s)
      長谷川功
    • Organizer
      第25回真鶴セミナー(生涯教育認定事業NO.12728)
    • Place of Presentation
      厚木
    • Year and Date
      2009-08-29
    • Related Report
      2009 Annual Research Report
  • [Presentation] Pupillary light reflexes to color stimuli in rats using a newly developed video pupilometer with a diffuse illumination system2009

    • Author(s)
      Iijima A.Haida M.Iida S.Sonoda S, Hasegawa I
    • Organizer
      IUPS2009
    • Place of Presentation
      京都
    • Year and Date
      2009-07-28
    • Related Report
      2009 Annual Research Report
  • [Presentation] 前脳のGABA受容体による自律機能の調節2009

    • Author(s)
      山口賢一、山田貴穗、濱齊、渡辺賢一、長谷川功
    • Organizer
      第47回新潟高血圧談話会
    • Place of Presentation
      新潟
    • Year and Date
      2009-07-10
    • Related Report
      2009 Annual Research Report
  • [Presentation] 映像酔いによる脳血流変化と心理スコアの関係2009

    • Author(s)
      飯島淳彦, 木竜徹, 鵜飼一彦, 長谷川功, 板東武彦
    • Organizer
      第48回日本生体医工学会
    • Place of Presentation
      東京
    • Year and Date
      2009-04-23
    • Related Report
      2009 Annual Research Report
  • [Presentation] Simultaneous recording of visual cortical response by a meshelectrode array and an intracortical microelectrode2009

    • Author(s)
      Toda H, Sawahata H, Suzuki T, Watanabe H, Isa T, Hasegawa I.
    • Organizer
      Soc Neurosci Abstr 35,770.20
    • Place of Presentation
      Chicago,USA
    • Related Report
      2010 Final Research Report
  • [Presentation] Pupillary and vergence responses to the cognition of radial optic flow., Pupil Informatics: Pupil Response Mechanisms2008

    • Author(s)
      Iijima A., Ukai K., Tsujimura S., Torii M., Hi ramoto S., Hasegawa I., Bando T
    • Organizer
      Visual Performance and Clinical Applications
    • Place of Presentation
      London, UK
    • Related Report
      2008 Annual Research Report
  • [Book] 局所フィールド電位の全脳同時記録(ブレインサイエンス・レビュー2010(編集))(ブレインサイエンス振興財団)(伊藤正男・川合述史)2010

    • Author(s)
      長谷川功
    • Publisher
      (株)クバプロ
    • Related Report
      2010 Final Research Report
  • [Book] ブレインサイエンス・レビュー20102010

    • Author(s)
      長谷川功
    • Publisher
      (株)クバプロ
    • Related Report
      2010 Annual Research Report
  • [Patent(Industrial Property Rights)] 網状生体電極アレイ2010

    • Inventor(s)
      長谷川功(寄与率60%)、鈴木隆文(同40%)
    • Industrial Property Rights Holder
      新潟大学1東京大学
    • Filing Date
      2010-07-30
    • Related Report
      2010 Annual Research Report
  • [Patent(Industrial Property Rights)] 意志伝達支援装置2009

    • Inventor(s)
      長谷川功(寄与率70%)、神谷之康(同30%)
    • Industrial Property Rights Holder
      新潟大学/ATR
    • Filing Date
      2009-04-27
    • Related Report
      2010 Final Research Report
  • [Patent(Industrial Property Rights)] 網状生体電極アレイ2009

    • Inventor(s)
      長谷川功(寄与率60%)、鈴木隆文(同40%)
    • Industrial Property Rights Holder
      新潟大学/東京大学
    • Filing Date
      2009-07-30
    • Related Report
      2010 Final Research Report
  • [Patent(Industrial Property Rights)] 意志伝達支援装置2009

    • Inventor(s)
      長谷川功(寄与率70%)、神谷之康(同30%)
    • Industrial Property Rights Holder
      新潟大学ATR
    • Filing Date
      2009-04-27
    • Related Report
      2009 Annual Research Report
  • [Patent(Industrial Property Rights)] 網状生体電極アレイ2009

    • Inventor(s)
      長谷川功(寄与率60%)、鈴木隆文(同40%)
    • Industrial Property Rights Holder
      新潟大学東京大学
    • Filing Date
      2009-07-30
    • Related Report
      2009 Annual Research Report

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Published: 2008-04-01   Modified: 2016-04-21  

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