2010 Fiscal Year Final Research Report
Proteolysis in the Regulation of Biological Processes
| Project Area | Proteolysis in the Regulation of Biological Processes |
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| Project/Area Number |
18076008
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| Research Category |
Grant-in-Aid for Scientific Research on Priority Areas
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| Allocation Type | Single-year Grants |
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| Review Section |
Biological Sciences
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| Research Institution | Tokyo Medical and Dental University |
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Principal Investigator |
MIZUSHIMA Noboru Tokyo Medical and Dental University, 大学院・医歯学総合研究科, 教授 (10353434)
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| Co-Investigator(Kenkyū-buntansha) |
SORIMACHI Hiroyuki 東京都医学研究機構, 東京都臨床医学総合研究所, 参事研究員 (10211327)
IWAI Kazuhiro 大阪大学, 生命機能研究科, 教授 (60252459)
SAKAI Yasuyoshi 京都大学, 農学研究科 (60202082)
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| Co-Investigator(Renkei-kenkyūsha) |
KOMINAMI Eiki 東京医科歯科大学
YOSHIDA Masasuke 東京医科歯科大学
NAGATA Kazuhiro 東京医科歯科大学
TANAKA Keiji 東京医科歯科大学
UCHIYAMA Yasuo 東京医科歯科大学
OHSUMI Yoshinori 東京医科歯科大学
SUZUKI Koichi 東京医科歯科大学
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| Project Period (FY) |
2006 – 2011
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| Keywords | タンパク質分解 / ユビキチン / オートファジー / カルパイン / プロテアーゼ / プロテオリシス |
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| Research Abstract |
This Grant-in-Aid for Scientific Research on Priority Areas "Proteolysis in the Regulation of Biological Processes" aimed to study the control mechanism for intracellular degradation systems and their biological and pathophysiological significance. While we coordinate our research, we promoted the establishment of our exchange of views and the development of young researchers in our research community through our unique discussion website "Proteolysis Forum", as well as annual meeting and symposia.
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