• Search Research Projects
  • Search Researchers
  • How to Use
  1. Back to project page

2016 Fiscal Year Final Research Report

Functions and molecular mechanisms of membrane trafficking in biogenesis and functions of cell wall

Planned Research

  • PDF
Project AreaPlant cell wall as information-processing system
Project/Area Number 24114003
Research Category

Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)

Allocation TypeSingle-year Grants
Review Section Biological Sciences
Research InstitutionNational Institute for Basic Biology (2016)
The University of Tokyo (2012-2015)

Principal Investigator

UEDA Takashi  基礎生物学研究所, 細胞動態研究部門, 教授 (10311333)

Co-Investigator(Renkei-kenkyūsha) UEMURA Tomohiro  東京大学, 大学院理学系研究科, 助教 (90415092)
FUJIMOTO Masaru  東京大学, 大学院農学生命研究科, 准教授 (60554475)
EBINE Kazuo  基礎生物学研究所, 細胞動態研究部門, 助教 (90590399)
Project Period (FY) 2012-06-28 – 2017-03-31
Keywords膜交通 / 細胞壁 / セルロース合成酵素複合体 / イノシトールリン脂質 / エンドサイトーシス / 液胞 / Rab GTPase
Outline of Final Research Achievements

We analyzed mechanisms of cell wall construction and cell wall functions with various techniques, including super-resolution microscopy, biochemistry, and genetics. We succeeded in fine-resolution imaging of transport of the cellulose synthase complex, which is distinctly dependent on PI3K and PI4K. We also analyzed RABA/RAB11 functions in endocytosis of FLS2 to demonstrate functional diversification of RABA/RAB11 members. Furthermore, we demonstrated that the plant vacuolar transport pathway is distinctly regulated from yeasts and animals, which plays a pivotal role in cell wall integrity. Evolutionary cell biological analyses of the membrane trafficking system using the liverwort, Marchantia polymorpha, is also currently underway.

Free Research Field

植物分子細胞生物学

URL: 

Published: 2018-03-22  

Information User Guide FAQ News Terms of Use Attribution of KAKENHI

Powered by NII kakenhi