Development of Dynamical Ordering of Artificial Molecules by Mimicking Biomolecular Systems

2017 Fiscal Year Final Research Report

• Project Area: Dynamical ordering of biomolecular systems for creation of integrated functions
• Project/Area Number: 25102007
• Research Category: Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
• Allocation Type: Single-year Grants
• Review Section: Science and Engineering
• Research Institution: The University of Tokyo (2016-2017); Tohoku University (2013-2015)
• Principal Investigator: Sato Sota 東京大学, 大学院理学系研究科(理学部), 特任准教授 (40401129)
• Project Period (FY): 2013-06-28 – 2018-03-31
• Keywords: 動的秩序化 / 自己組織化 / 球状錯体 / サイボーグ超分子 / 相転移 / 巨大分子 / 単結晶X線構造解析 / 生命分子科学

Outline of Final Research Achievements

The natural mechanism that has been unveiled by molecular life science was translated into artificial system, and the dynamic element in nature was adopted into conventional method to synthesize static multicomponent structures. The limit of the conventional method was overcome, and a new category of molecules including one with the world's largest component number was developed. Specific function and property were expressed from the unique structures. Using the phase transition in the ordering process, where the structure is largely switched with time development, an artificial molecular system that mimics the ordering of protein transport vesicles was created. By the introduction of fluctuating biomolecules on the complex skeleton, a cyborg supramolecule in which artificial molecules and biomolecules were hybridized was developed. The unique biologically relevant functions were developed through precise molecular designs.

Free Research Field

錯体化学・有機化学l