1992 Fiscal Year Final Research Report Summary
Environmental Chemicals and Allergic Conjunctivitis: Pollinosis.
| Project/Area Number |
02454407
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| Research Category |
Grant-in-Aid for General Scientific Research (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Ophthalmology
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| Research Institution | Kitasato University |
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Principal Investigator |
MIYATA Mikio 北里大学, 医学部, 教授 (30050438)
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| Co-Investigator(Kenkyū-buntansha) |
OKU Hidehiro 北里大学, 医学部, 助手 (90177163)
FUKUSHIMA Kazuya 北里大学, 医学部, 助手 (60199205)
HORIUCHI Koushi 北里大学, 医学部, 助手 (80190239)
NAMBA Tatsuto 北里大学, 医学部, 講師 (70164514)
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| Project Period (FY) |
1990 – 1992
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| Keywords | Allergic conjunctivitis / Environment / Organophosphorous pesticide / p-Dichlorobenzene / Trihalomethane / Organochlorine herbicide / Food additives / Electromagnetic wave |
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| Research Abstract |
In the recent years, the number of pollen induced allergic patients have increased. The reason for this could not be explained only by the increasing amount of cedar pollen antigen. Some environmental factors might cause the increase of disease. The present project was conducted to elucidate the factors.
The allergic conjunctivitis experimentally induced by cedar pollen was apparently aggravated by extremely low concentration of organophosphorous pesticides, organochlorine herbicide, cigarette smoke, trihalomethane, p-dichlorobenzene, food preservatives and food colors such as red No.3 and turtoladin. The aggravating effects of these chemicals were rather weak in higher concentration. Exposure to cathode ray tube of visual detector terminal also aggravated the allergic conjunctivitis. Environmental chemicals as well as electromagnetic waves seemed to derange our immunological condition.
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