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[Publications] Kuwata T.,Hayami,M.et al.: "The rapid spread of recombinants during a natural in vitro infection with two Human Immunodeficiency Virus type 1 strains." J.Virol. 71. 7088-7091 (1997)
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[Publications] Enose,Y.,Hayami,M.et al.: "Restriction of viral population by Intravaginal Infection of simian Immunodeficiency viruses in Macaque Monkeys." Arch.Virol.142. 37-51 (1997)
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[Publications] Murayama,Y.,Mukai,R.,Hayami,M.et al.: "CD4 and CD8 expressions in African green monkey helper T lymphocytes : Implication for resistance to SIV infection." International Immunology. 9(6). 843 (1997)
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[Publications] Chen,J.,Hayami,M.et al.: "Replication of HIV-1,SIVmac and Chimeric HIV-1/SIVmac Viruses having env genes derived from macrophage-tropic viruses : an indication od different mechanisms of macrophage-tropism in human and monkey cells." J.Gen.Viol.(in press).
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[Publications] Ido,E.,Hayami,M et al.: "Infection of an HIV-1/SIVmac chimeric virus having HIV-1 env to Macaque monkeys via Vaginal Cavity." Microbiol. & Immunol.41(3). 277-280 (1997)
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[Publications] Igarashi T.,Mukai,R.,Hayami M.et al.: "Protection of monkeys vaccinated with vpr-and/or nef-defective simian immunodeficiency virus strain mac/human immunodeficiency virus type 1 chimeric viruses : a potential candidate live-attenuated human AIDS vaccine." J.Gen.Virol.78. 985-989 (1997)
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[Publications] Bogers,WH.Hayami,M.et al.: "Comparison of in vitro and in vivo infectivity of different clade B HIV-1 envelope chimeric simian/human immunodeficiency virus in Macaca mulatta." Virology. 236. 110 (1997)
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[Publications] Iida,T.,Hayami,M.et al.: "Fas antigen expression and apoptosis of lymphocytes in macaques infected with simian immunodeficiency virus strain mac" Arch.of Virol.(in press).
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[Publications] Isaka,Y.,Hayami,M.et al.: "Construction of the chimeric virus clone of simian immunodeficiency virus possessing the sensitive to nonnucleoside reverse transcriptase inhibitor." Microbiol. & Imml.(in press).
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[Publications] Haga,T.,Hayami,M.et al.: "A new approach to AIDS research and prevention : The use of gene-mutated HIV-1/SIV chimeric viruses for anti-HIV-1 live attenuated vaccines." Microbiol. & lmmunol.(in press).
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[Publications] Hayami,M.et al.: "Gene-mutated HIV-1/SIV chimeric viruses as AIDS live attenuated vaccines for potential human use." Leukemia. (in press).
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[Publications] Fuji,Y.,Mukai,R.et al.: "Efficacy of 6-chloro-2',3'-dideoxy guanosine (6-Cl-ddG) on an ARC/AIDS rhesus macaque (Macaca mulatta) infected with simian immuno-deficiency virus" Exp.Anim.46. 83-87 (1997)
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[Publications] Otani I.,Mukai,R., et al.: "Effects of 6-chloro-2',3'-dideoxy guanosine (6-CI-ddG) in surface lymph nodes of rhesus momkeys (Macaca mulatta) chronically infected with simian immuno deficiency virus (SIVmac239)." J.Vet.Med.Sci.59. 891-896 (1997)
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[Publications] Fuji,Y.,Mukai,R., et al.: "Efficacy of 6-chloro-2',3'-dideoxy guanosine (6-CI-ddG) on Rhesus macaque chronically infected with simian immuno deficiency virus (SIVmac239)." J.Acquir.Immune.Defic.Syndr.Hum.Retrovirol.16. 313-317 (1997)
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[Publications] Fuji,Y.,Mukai,R., et al.: "Antiviral effects of 6-chloro-2',3'-dideoxy guanosine (6-Cl-ddG) in rhesus monkeys acutely infected with SIV" Antiviral Chem. & Chemother. 9. 85-92 (1998)
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[Publications] Shimojima,M.,Mikami,T., et al.: "Generation of monoclonal antibodies against a feline CD antigen (CD4) expressed by a recombinant baculovirus." J.Vet.Med.Sci.59. 467-469 (1997)
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[Publications] Inada,G.,Mikami,T., et al.: "Phylogenetic analysis of feline immunodeficiency virus isolated from cats in Taiwan." Arch.Virol.149. 1459-1467 (1997)
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[Publications] Yamamoto,H.,Nikami,T., et al.: "Immunological and histological disorders in cats experimentally infected with feline immunodeficiency virus subtype B (TM2 strain)." Vet Microbiol.57. 313-324 (1997)
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[Publications] Ikeda,Y.,Mikami,T., et al.: "The effects of treatment with chemical agents or infection with feline viruses on protein-binding properties of the feline immunodeficiency virus long terminal repeat." Virus Res.51. 203-212 (1997)
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[Publications] Ikeda,Y.,Mikami,T., et al.: "Protein-binding properties of the putative AP-1 and ATF sequences in the feline immunodeficiency virus long terminal repeat." J.Gen.Virol.78. 95-99 (1997)
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[Publications] Shimojima,M.,Mikami,T., et al.: "Expansion of CD8α+β-cells in cats infected with feline immunodeficiency virus" J.Gen.Virol.78. 91-94 (1997)
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[Publications] Inoshima,Y.,Mikami,T., et al.: "Cross virus neutralizing antibodies against feline immunodeficiency virus genotypes A,B,C,D and E." Arch.Virol.(in press)
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[Publications] Shimojima,M.,Mikami,T., et al.: "Characterization of Anti-feline CD8 monoclonal antibodies." Vet Immunol.Immunopathol.(in press).
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[Publications] Inoshima,Y.,Mikami,T., et al.: "in vivo functions of the auxiliary genes and reguratory elements of feline immunodeficiency virus." Vet.Microbiol.(in press).
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[Publications] Inoshima,Y.,Mikami,T., et al.: "The roles of vif and ORF-A genes and AP-1 binding site in in vivo replication of feline immunodeficiency virus." Arch.Virol.(in press).
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[Publications] Kohmoto,K.,Mikami,T., et al.: "Eight-year observation and comparative study of specific pathgen-free cats experimentally infected with feline immunodeficiency virus (FIV) subtypes A and B : terminal acquired immunodeficiency syndrome in a cat infected with FIV petaluma strain." J.Vet.Med.Sci.(in press).
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[Publications] Sato,E.,Mikami,T., et al.: "Construction of a recombinat feline herpesvirus type 1 expressing Gag precursor protein of feline immunodeficiency virus." Arch.Virol.(in press).
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[Publications] Tomonaga,K.,Mikami,T., et al.: "Characterization of an integrase mutant of feline immunodeficiency virus" Arch.Virol.(in press).
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[Publications] Hano,T.,Kinashi,T., et al.: "IL-4 induces homotypic aggregation of human culture mast cells by promoting LFA-1/ICAM-1 adhesion molecules." Blood. 89. 3296-3302 (1997)
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[Publications] Kawano,Y.,Tanaka,Y., et al.: "Mutational analysis of HIV-1 accessory genes : Requirement of a site in the nefgene for HIV-1 replication in activated CD4_+ T cells in vitro and in vivo." Journal of Virology. 71. 8456-8466 (1997)
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[Publications] Koyanagi,Y.,Tanaka,Y., et al.: "Primary human immunodeficiency virus type 1 viremia and central nervous system invasion in a novel hu-PBL-immunodeficient mouse strain." Journal of Virology. 71. 2417-2424 (1997)
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[Publications] Tanaka,Y., et al.: "Productive and lytic infection of human CD4_+type 1 helper T cells with macrophage-tropic human immunodeficiency virus type 1." Journal of Virology. 71. 465-470 (1997)
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[Publications] Asano,M.,Iwakura,Y.et al.: "Growth retardation and early death of b-1,4-galactosyltransferase knockout mice with augmented proliferation and abnormal differentiationof epithelial cells." EMBO J.16. 1850-1857 (1997)
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[Publications] Tagawa,Y.,Iwakura,Y.et al.: "Suppression of Concanavalin A induced hepatitis in IFN-g-/-,but not in TNF-a-/-,mice : role for IFN-g in activating apoptosis of hepatocytes." J.Immunol.159. 1418-1428 (1997)
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[Publications] Ozaki,H.,Iwakura,Y.et al.: "TNF-a,but not IL-1,II-6,or IFN-g is the maior mediator of LPS-induced HIV.activation in mice transgenic for HIV" J.Interferon Cytokine Res.17. S105 (1997)
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[Publications] Yoshimoto,T.,Iwakura,Y.et al.: "Interleukin 18 together with interleukin 12 inhibits IgE production by induction of interferon-g production from activated B cells." Proc.Natl.Acad.Sci.USA. 94. 3948-3953 (1997)
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[Publications] Kishi,S.,Iwakura,Y.et al.: "Resistance to Fas-mediated apoptosis of peripheral T cells in human T lymphocyte virus typel (HTLV-1) transgenic mice with autoimmune arthropathy." J.Exp.Med.186. 57-64 (1997)
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[Publications] Hayami,M.et al.: "SIV/HIV-1 chimeric viruses having HIV-1 env gene : a new animal model and a candidate for attenuated live vaccine." Leukemia,vol.11 : 95-97,ed.Ikawa,Y.,STOCKTON,UK, 95-97 (1997)