1998 Fiscal Year Final Research Report Summary
DEVELOPMENT OF 350MHz PULSED EPR SPECTROMETER
| Project/Area Number |
08555002
|
|---|
| Research Category |
Grant-in-Aid for Scientific Research (B)
|
| Allocation Type | Single-year Grants |
|---|
| Section | 展開研究 |
|---|
| Research Field |
Applied materials science/Crystal engineering
|
|---|
| Research Institution | YAMAGATA UNIVERSITY |
|---|
Principal Investigator |
ONO Mitsuhiro YAMAGATA UNIVERSITY,ELECTRICAL AND INFORMATION ENGINEERING,PROFESSOR, 工学部, 教授 (60007010)
|
|---|
| Co-Investigator(Kenkyū-buntansha) |
HANIWA Masatoshi TOSHIBA CO.LTD.ELECTRICAL ENGINEERING,TEAM READER OF RESEARCH, 那須工場, 研究チームリーダー
HIRATA Hiroshi YAMAGATA UNIVERSITY,ELECTRICAL AND INFORMATION ENGINEERING,ASSOCIATE PROFESSOR, 工学部, 助教授 (60250958)
SHIMOYAMA Yuhei HOKKAIDO UNIVERSITY OF EDUCATION,PHYSICS,PROFESSOR, 教育学部, 教授 (50123948)
|
|---|
| Project Period (FY) |
1996 – 1998
|
| Keywords | ELECTRON PARAMAGNETIC RESONANCE (EPR) / ELECTRON SPIN RESONANCE (ESR) / IN VIVO MEARSUREMENT / ELECTRON SPIN ECHO (ESE) / PULSE / RELAXATION TIME CONSTANT |
|---|
| Research Abstract |
The study of the behavior of free radicals in a living body has recently become very important in pathology, physiology and pharmacology, We have developed a 350MHz pulsed EPR(Electron paramagnetic resonance) spectrometer especially used for in situ measurement of a rat's whole body, and obtained the following results.
(1) Optimum pulse width and quality factor Q of the resonator are 10-68ns and 10-60, respectively, for the relaxation time constant T_2=10-100ns of bio-radicals, and 68-158ns and 60-280, respectively, for T_2=100-800ns of radicals in solid materials.
(2) Using this spectrometer, the signal of electron spin echo(ESE) was detected for the sample of gamma-irradiated quartz powder. Signal voltage was 3-5mV for 1,400-1 , 600ns of pulse interval.
(3) Relaxation time constant of gamma-irradiated quartz is estimated to be 778 ns, This value is nearly equal to 759 ns obtained at 1.3 GHz in our laboratory.
(4) It is required to reduce the Q value of the resonator to make the measurement of bio radicals possible.
|
