2001 Fiscal Year Final Research Report Summary
INVESTIGATION OF THE BRAIN FUNCTION OF THE VARIOUS KINDS OF DISORDERD SUBJECTS BY COMPLETE NONINVASIVE BRAIN MAPPING TECHNIQUE
| Project/Area Number |
11351001
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| Research Category |
Grant-in-Aid for Scientific Research (A)
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| Allocation Type | Single-year Grants |
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| Section | 展開研究 |
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| Research Field |
実験系心理学
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| Research Institution | JAPAN WOMEN'S UNIVERSITY |
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Principal Investigator |
KAWACHI Juro JAPAN WOMEN'S UNIVERSITY, FACLUTY OF HOME ECONOMICS, PROFESSOR, 家政学部, 教授 (30083710)
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| Co-Investigator(Kenkyū-buntansha) |
DAIROKU Hitoshi MUSASHlNO WOMEN'S UNIVERSITY, FACULTY OF HUMAN STUDIES, ASSOCIATE PROFESSOR, 人間関係学部, 助教授 (10251323)
TORII Toshiko FACULTY OF INTEGRATED ARTS AND SOCIAL SCIENCES, PROFESSOR, 人間社会学部, 教授 (70060671)
KAWAMURA Mitsuru SHOWA UNIVERSITY, FACULTY OF MEDICINE, PROFESSOR, 医学部, 教授 (20161375)
NOCHI Masahiro TElKYO UNIVERSITY, FACULTY OF LETTERS, LECTURER, 文学部, 講師 (30292717)
ODA Kouichi TOKYO WOMEN'S UNIVERSITY, FACULTY OF CURRENT CULTURES, PROFESSOR, 現代文化部, 教授 (60169307)
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| Project Period (FY) |
1999 – 2001
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| Keywords | optical topography / noninvasive brain mapping / portability / nonrestraint / tapping movement / sensorimotor cortex / grammatical task / Broca's area |
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| Research Abstract |
The purpose of this study, started since 1999, is to gain valid informations about the brain activity of the several kinds of disordered subjects in order to facilitate the education, rehabilitation, and recovery of function by using newly developed completely noninvasive brain mapping technique, optical topography. The optical topography is a new measurement method for functional imaging of brain activity accompanied by regional concentration changes in oxy- and deoxy-hemoglobin in the cerbral cortex. Optical topography has several advantages compared with other functional imaging techniques such as PET, fMRI, and MEG, mainly portability and decreased sensitivity to subject movement. Since this study is one of the earliest studies putting the optical topography to practical use, accumulating the fundamental data about applicability of this technique to the disordered subjects was the important factor of this study.
1. Brain activity during finger tapping was measured by optic topography and fMRl and it was found that the center of the activation area obtained by using optical topography is displaced by less than 15 mm from that obtained by using fMRI.
2. It is found that the near infra red rays used by the optical topography is completely noninvasive to human skin and it is confirmed that the optical topography is applicable to human infants.
3. The brain activity of occipital lobe of the sleeping newborn infants by using optical topography and it was found that there was spatially synchronizing spontaneous oscillation of the blood flow.
4. The brain activity of the normal adults during making grammatical judgements and spatial judgements by using optical topography and it was found that total hemoglobin increased to Broca's area when subjects made grammatical judgements.
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