2002 Fiscal Year Final Research Report Summary
Developing Softwares for Molecular Phylogenetics
| Project/Area Number |
12554037
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| Research Category |
Grant-in-Aid for Scientific Research (B)
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| Allocation Type | Single-year Grants |
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| Section | 展開研究 |
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| Research Field |
系統・分類
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| Research Institution | The Institute of Statistical Mathematics |
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Principal Investigator |
HASEGAWA Masami Institute of Statistical Mathematics, Department of Prediction Theory, Professor, 予測制御研究系, 教授 (60011657)
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| Co-Investigator(Kenkyū-buntansha) |
GOTOH Osamu Computational Biology Research Center, National Institute of Advanced Industrial Science and Technology, Project leader, 生命情報, 主任研究員 (40142111)
SHIMODAIRA Hidetoshi Tokyo Institute of Technology, Lecturer, 情報理工学研究科, 講師 (00290867)
HASHIMOTO Tetsuo University of Tsukuba, Institute of Biological Sciences, Professor, 生物科学系, 教授 (50208451)
KISHINO Hirohisa University of Tokyo, Graduate School of Agriculture and Life Sciences, Professor, 農学生命科学研究科, 教授 (00141987)
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| Project Period (FY) |
2000 – 2002
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| Keywords | molecular phylogenetics / model misspecification / phylogenetic inference / tree selection / divergence time / molecular clock / adaptive evolution / eutherian mammal |
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| Research Abstract |
It is prerequisite to establish the phylogenetic relations among organises before studying biological evolution and biodiversity. We developed methods for inferring molecular phylogenies based on the likelihood approach and applied them tb various phylogenetic problems ;
(1) The effect of model misspecification in phylogenetic inference,
(2) Modelling in the phylogenetic inference ofmulti-gene data,
(3) Tests of phylogenetic tree selection,
(4) Methods for estimating divergence times without assuming a molecular clock,
(5) Detecting adaptive molecular evolution,
(6) Phylogenetic evolution of eutherian mammals
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