2001 Fiscal Year Final Research Report Summary

Transfer of egg probeins into breast milk

Research Project

Project/Area Number	12660125
Research Category	Grant-in-Aid for Scientific Research (C)
Allocation Type	Single-year Grants
Section	一般
Research Field	食品科学・栄養科学
Research Institution	Junior College of Kyoto Women's University
Principal Investigator	NARITA Hiroshi Dept. of Life Science, Junior College of Kyoto Women's University, Professor, 短期大学部・生活科学科, 教授 (30155999)
Project Period (FY)	2000 – 2001
Keywords	food allergy / allergen / egg / ovomucoid / breast milk / monoclonal antibody / immune complex / secretory IgA
Research Abstract	On gel-filtration, the major food allergen, ovomucoid (28 kDa) in human breast milk was eluted only at the fractions corresponding to a molecular weight of about 450 kDa. Almost same elution profile as that for ovomucoid was obtained for its immune complex with sIgA. Similar results, suggesting the occurrence of food allergens as immune complexes with sIgAs have been also observed for other food allergens in breast milk. Relationship between the presence of allergens in mother's milk and allergic symptoms of their babies should be discussed hereafter in consideration of not only the level but also the molecular feature of allergens.

(4 results)