2002 Fiscal Year Final Research Report Summary
EPIDEMIOLOGICAL STUDY OF RELATIONSHIP BETWEEN PROSTATE VOLUME AND VITAMIN A.
| Project/Area Number |
12671559
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Urology
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| Research Institution | JIKEI UNIVERSITY SCHOOL OF MEDICINE |
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Principal Investigator |
ONISHI Tetsuro JIKEI UNIVERSITY SCHOOL OF MEDICINE Associated Professor,Department of Urology,, 医学部, 助教授 (60138724)
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| Co-Investigator(Kenkyū-buntansha) |
ISAO Ikemoto Associated Professor, Department of Urology,Jikei University School of Medicine, 医学部, 助教授 (40159645)
TAKASHI Hatano Lecturer, Department of Urology, Jikei University School of Medicine, 医学部, 講師 (70256436)
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| Project Period (FY) |
2000 – 2002
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| Keywords | benign prostate hypertrophy / epidemiological study / vitamin A / beta carotene |
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| Research Abstract |
To evaluate the relationship between the prostate volume and diet especially vitamin A, we conducted an epidemiological study by questionnairing and blood examination.This questionnaire contained 6 items which addressed eating habits, smoking and alcohol drinking.. Blood examination (retinal, beta-carotene, retinol binding protein, total cholesterol and trigliceride) and measurement of the prostate volume were performed in 160 subjects aged 50 years or more. The prostate volume was examined by transrectal ultra sonography (TRUS) and classified into the normal prostate and benign prostate hypertrophy (BPH).
In this study, the statistically significant characteristics of the BPH group were the low smoking rate and high serum beta-carotene levels.Retinol and retinol binding protein showed no significant difference.
These results suggested that serum beta-carotene has some influence on the prostate volume and occurrence of disease.
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