2001 Fiscal Year Final Research Report Summary
THE CONTROL MECHANISM OF NO REFLOW PHENOMENON IN FETAL ISCHEMIC CARDIOCYTE
| Project/Area Number |
12671635
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Obstetrics and gynecology
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| Research Institution | NIPPON MEDICAL SCHOOL |
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Principal Investigator |
ISHIKAWA Gen NIPPON MEDICAL SCHOOL, OBSTETRICS AND GYNECOLOGY, INSTRUCTOR, 医学部, 助手 (20287767)
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| Co-Investigator(Kenkyū-buntansha) |
SAWA Rintaro NIPPON MEDICAL SCHOOL, OBSTETRICS AND GYNECOLOGY, INSTRUCTOR, 医学部, 講師 (30267174)
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| Project Period (FY) |
2000 – 2001
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| Keywords | adenosine / fetus / coronary artery / no reflow phenomenon / platelets |
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| Research Abstract |
[PURPOSE] The purpose of this study is to evaluate the protective effect of fetal adenosine on the maintenance of blood flow in fetal ischemic cardiocyte.
[METHOD] We measured plasma adenosine and blood flow in fetal ischemic cardiocyte, then evaluate the relationship between these parameters.
[RESULTS] The elevation of plasma adenosine was associated with an increase of blood flow in fetal ischemic cardiocytes.
[CONCLUSION] This study has suggested that plasma adenosine may play role in the regulation of blood flow in fetal cardiocytes, which eventually inhibit the no reflow phenomenon in fatal cardiocytes.
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