2004 Fiscal Year Final Research Report Summary
Influence of placement position and designing of removable partial denture on oral sensation
| Project/Area Number |
13307056
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| Research Category |
Grant-in-Aid for Scientific Research (A)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
補綴理工系歯学
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| Research Institution | Tokyo Medical and Dental University |
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Principal Investigator |
OHYAMA Takashi Tokyo Medical and Dental University, Graduate School, Professor, 大学院・医歯学総合研究科, 教授 (50064366)
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| Co-Investigator(Kenkyū-buntansha) |
MORIMOTO Toshifumi Matsumoto Dental University, Comp Dent Res Labo, Professor, 総合歯科医学研究所, 教授 (20028731)
KONO Shoji Niigata University, Graduate School of Dentistry, Professor, 大学院・医歯学総合研究科, 教授 (50014098)
KATAYAMA Yoshifumi Tokyo Medical and Dental University, Professor, 難治疾患研究所, 教授 (20014144)
NOKUBI Koji Osaka University, Graduate School of Dentistry, Professor, 大学院・歯学研究科, 教授 (80028753)
KOYANO Kiyoshi Kyusyu University, Graduate School of Dentistry, Professor, 大学院・歯学研究院, 教授 (50195872)
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| Project Period (FY) |
2001 – 2004
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| Keywords | oral sensation / umami / glutamine amino aid / gustatory response / bolus formation ability / pressure-pain threshold / occlusal vertical dimension / trigeminal mesencephalic nucleus |
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| Research Abstract |
This study aimed to investigate the effects of different shapes of removable dentures on oral sensation, and to identify comfortable position and designing of major connectors.
Four different cross sectional form and different placement position of experimental palatal straps were delivered to 6 healthy subjects and examined as for lingual tactile sensation with questionnaire. The results were that with the knife-edged marginal shape of cross sectional form and the symmetrical form at the occlusal view of major connector exihibited less uncomfortable lingual tactile sensation.
When applying different thickness plates to 10 healthy dentulous subjects, with the thinner experimental metal plates, it showed more sensitive gustatory response than with the thicker metal or resin plates.
Two types of new method to evaluate the ability of mastication were developed and were applied to the partial edentulous patients with dentures. One was the method to analyze bolus formation ability by counting the number of rice cracker chewing strokes. Another was to analyze the amount of umami in saliva solution by measuring the glutamine amino acid in mastication of tangle at the molar teeth.
As to the pressure pain threshold(PPT) of edentulous oral mucosa, denture-wearing patients exhibited 40% lower value of PPT than non-denture-wearing patients.
In guinea pig experiment the neuronal mechanism of adjusting occlusal vertical dimension was investigated by physiological method. And the trigeminal mesencephalic nucleus were proved to be involved in the regulation of the occlusal vertical dimension. Raising or reducing occlusal vertical dimension alters the length of jaw-closing muscles, resulting in changing the sensitivity of the muscle spindles.
It was suggested that oral sensation and oral function are closely related with each other and consideration of oral sensation is necessary for the designing of removavle partial denture as much as retentive force and distribution of functional load.
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[Journal Article] A new cytochemical method for ultrastructural localization of Co^<2+> in rat hippocampal CA1 pyramidal neurons in vitro.2004
Author(s)
Tanaka, E., Ishii, K., Akagi, T., Hirai, K., Motelica-Heino, I., Katayama, Y., Higashi, H., Hashikawa, T., Tsuji, S
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Journal Title
J.Neurosci.Method 135
Pages: 1-8
Description
「研究成果報告書概要(和文)」より
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[Journal Article] Aquaporin-2 trafficking is regulated by PDZ-domain containing protein SPA-12004
Author(s)
Noda, Y., Horikawa, S., Furukawa, T., Hirai, K., Katayama, Y., Asai, T., Kuwahara, M., Katagiri, K., Kinashi, T., Hattori, M., Minato, N., Sasaki, S.
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Journal Title
FEBS Letters 568
Pages: 139-145
Description
「研究成果報告書概要(和文)」より
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[Journal Article] A new cytochemical method for ultrastructural localization of Co^<2+> in rat hippocampal CA1 pyramidal neurons in vitro.2004
Author(s)
Tanaka, E., Ishii, K., Akagi, T., Hirai, K., Motelica-Heino, I., Katayama, Y., Higashi, H., Hashikawa, T., Tsuji, S.
-
Journal Title
J.Neurosci.Method 135
Pages: 1-8
Description
「研究成果報告書概要(欧文)」より
-
[Journal Article] Aquaporin-2 trafficking is regulated by PDZ-domain containing protein SPA-1.2004
Author(s)
Noda, Y., Horikawa, S., Furukawa, T., Hirai, K., Katayama, Y., Asai, T., Kuwahara, M., Katagiri, K., Kinashi, T., Hattori, M., Minato, N., Sasaki, S.
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Journal Title
FEBS Letters 568
Pages: 139-145
Description
「研究成果報告書概要(欧文)」より
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