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2002 Fiscal Year Final Research Report Summary

Ultrasonic wave assisted micro bubble manipulation and it application

Research Project

Project/Area Number 13650454
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Measurement engineering
Research InstitutionFaculty of Engineering, Gunma University

Principal Investigator

YAMAKOSHI Yoshiki  Gunma University, Faculty of Engineering, Professor, 工学部, 教授 (10174640)

Co-Investigator(Kenkyū-buntansha) IDA Makoto  Gunma University, Faculty of Engineering, Postdoctor, 工学部, 中核的研究機関研究員
MASUDA Nobuyuki  Gunma University, Faculty of Engineering, Assistant, 工学部, 助手 (60323333)
Project Period (FY) 2001 – 2002
KeywordsUltrasonic waves / Micro bubbles / Radiation force / Bjerknes force / Trapping / Bubble manipulation / Ultrasonic contrast agent / 集合気泡
Research Abstract

Micro air bubbles with a diameter of several micrometers or less attract attention in the field of a medical diagnosis and medical treatment. The research representative of this research is reporting the result in which it might inquire over the past several years about manipulation of the particle by the ultrasonic wave. In this research, the following results were obtained based on these results. 1) The evaluation of cellular dynamics which made full use of a simulation. 2) Detailed experimental examination containing from a basic experiment to an animal experiment. 3) Development of the new application based on these knowledge. The concrete results are follows. 1) About numerical analysis, the code in the 3-dimensional completeness model in consideration of the influence of the surface tension of a cellular film is completed. 2) It analyzed about nonlinear vibration of the air bubbles in the case where two or more air bubbles exist. The experimental system which can transmit four independent ultrasonic waves simultaneously based on a laboratory existing ultrasonic transmitting system was made. Examination about the influence erythrocyte affects cellular trapping, research of detailed cellular dynamics using the air bubbles were done.

  • Research Products

    (8 results)

All Other

All Publications (8 results)

  • [Publications] Y.Yamakoshi, Y.Ozawa, N.Chelly, Y.Kurita, N.Masuda: "Characterization of Secondary Ultrasonic Waves Radiated from Bubbles Based on Small-Bubble Trapping Pattern Analysis"Jpn.J.Appl.Phys.. Vol.41,No.5B. 3559-3562 (2002)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] N.Chelly, Y.Yamakoshi, Y.Sawada, T.Sakamaku, M.Ida, N.Masuda, Y.Ozawa: "Effects of Red Cells on Ultrasonic Wave Micro bubble Trapping"Jpn.J.Appl.Phys.. Vol.41,No.5A. 3145-3146 (2002)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] 山越芳樹: "特集-超音波エネルギーを使った治療法、"超音波によるマイクロバブルのトラッピング"超音波TECNO. Vol.14,No.1. 55-58 (2002)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] 山越芳樹: "超音波による微小気泡のハンドリング"日本音響学会誌. Vol.58,No.10. 659-662 (2002)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] Y.Yamakoshi, Y.Ozawa: "Holographic Visualization of Secondary Ultrasonic Waves Radiated from Micro Bubble"IEEE Int.Symp.Abstract. 323-324 (2002)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] Y. Yamakoshi, Y. Ozawa, N. Chelly, Y. Kurita and N. Masuda: "Characterization of Secondary Ultrasonic Waves Radiated from Bubbles Based on Small-Bubble Trapping Pattern Analysis"Jpn. J. Appl. Phys.. 41, No.5B. 3559-3562 (2002)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] N. Chelly, Y.Yamakoshi, Sa-wada, T. Sakamaku, M. Ida, N. Masuda and Y. Ozawa: "Effects of Red Cells on Ultrasonic Wave Micro bubble Trapping"Jpn. J. Appl. Phys.. 41, No.5A. 3145-3146 (2002)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] Y. Yamakoshi and Y. Ozawa: "Holographic Visualization of Secondary Ultrasonic Waves Radiated from Micro Bubble"IEEE Ultrasonics Int. Symp. Abstract. 323-324 (2003)

    • Description
      「研究成果報告書概要(欧文)」より

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Published: 2004-04-14  

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