2003 Fiscal Year Final Research Report Summary
STUDIES ON SOME FACTORS RESPOSIBLE FOR CONJUGATED LINOLEIC ACID CONTENT IN FOODS OF RUMINANT ORIGINS
| Project/Area Number |
13660269
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Zootechnical science/Grassland science
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| Research Institution | University of Miyazaki |
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Principal Investigator |
YAMAUCHI Kiyoshi UNIVERSTIY OF MIYAZAKI, FACULTY OF AGRICULTURE, PROFESSOR, 農学部, 教授 (90040865)
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| Co-Investigator(Kenkyū-buntansha) |
KAWAHARA Satoshi UNIVERSTIY OF MIYAZAKI, FACULTY OF AGRICULTURE, ASSISTANT PROFESSOR, 農学部, 助手 (30284821)
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| Project Period (FY) |
2001 – 2003
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| Keywords | Conjugated linoleic acid (CLA) / c9, t11 isomer of CLA / Foods of ruminant origins / Concentrate / Roughage ration / Precursor of c9, t11 isomer / Rumen liquor / Linoleic acid / α -Linolenic acid |
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| Research Abstract |
Conjugated linoleic acid (CLA) is a collective term used to describe one or more positional and geometric isomers of linoleic acid. Of the CLA isomers, cis9, trans11 isomer which is found primarily in ruminants amounts as much as 80〜90% of the total CLA content of foods of ruminant origins. The cis9, trans11 isomer of CLA has been shown in animals to have an anticarcinogenic property. It is believed that cis9, trans11 CLA isomer is produced in the rumen as intermediates in the biohydrogenation of dietary linoleic acid to stearic acid. Our works have demonstrated that the cis9, trans11 CLA contents of meat and fat from ruminants fed a relatively high roughage ration is significantly higher than those from ruminants fed a relatively high concentrate ration, with the results suggesting that α -linolenic acid present predominantly in pasture lipid might be involved in the formation of cis9, trans11 CLA.
Therefore, crashed corn high in linoleic acid and Italian ryegrass hay high in α -linolenic acid were incubated with rumen liquor culture. The yield of cis9, trans11 CLA from the Italian ryegrass was siginificantly higher than that from the crashed corn. This findings suggested the formation of cis9, trans11 CLA via α -linolenic acid. α -Linolenate was incubated with rumen liquor culture. The formation of cis9, trans 11 CLA from α -linolenate was first observed in the rumen liquor culture, and the pH value of the rumen liquor culture also influenced the metabolism. The results showed that α -linolenate incubated with rumen liquor culture produced three intermediate metabolites of which c9, t11, c15 octadecatrienoic acid might be involved in the formation of cis9, trans11 CLA in the rumen. The results obtained in the present study confirmed for the first time that in additoin to linoleic acid, α -linolenic acid present predominantly in pasture lipid may serve as a potential precursor of cis9, trans 11 CLA in the rumen.
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Research Products
(10 results)
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[Publications] Takenoyama, S., Kawahara, S., Muguruma, M., Murata, H., Yamauchi, K.: "Studies on the 9cis, 11trans conjugated linoleic acid contents of meat and dairy products."Animal Science Journal. Vol.72,No.1. 63-71 (2001)
Description
「研究成果報告書概要(和文)」より
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[Publications] Kawahara, S., Takenoyama, S., Nagato, C., Muguruma, M., Ito, T., Yamauchi, K.: "Evaluation of beef tallow as a naturalsource of conjugated linoleic acid."Animal Science Journal. Vol.73,No.6. 533-539 (2002)
Description
「研究成果報告書概要(和文)」より
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[Publications] Takenoyama, S., Kawahara, S., Muguruma, M., Murata, H.Yamauchi, K.: "Studies on the 9cis, 11trans conjugated linoleic acid contents of meat and dairy products."Animal Science Journal. Vol.72, No.1. 63-71 (2001)
Description
「研究成果報告書概要(欧文)」より
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[Publications] Kawahara, S., Takenoyama, S., Nagato, C., Muguruma, M., Ito, T., Yamauchi, K.: "Evaluation of beef tallow as a natural source of conjugated linoleic acid."Animal Science Journal. Vol.73, No.6. 533-539 (2002)
Description
「研究成果報告書概要(欧文)」より
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