2002 Fiscal Year Final Research Report Summary
Development of functional soft denture liners without environmental endocrine disruptors
| Project/Area Number |
13672036
|
|---|
| Research Category |
Grant-in-Aid for Scientific Research (C)
|
| Allocation Type | Single-year Grants |
|---|
| Section | 一般 |
|---|
| Research Field |
補綴理工系歯学
|
|---|
| Research Institution | HIROSHIMA UNIVERSITY |
|---|
Principal Investigator |
MURATA Hiroshi Hiroshima University, Graduate School of Biomedical Sciences, Research Associate, 大学院・医歯薬学総合研究科, 助手 (40229993)
|
|---|
| Co-Investigator(Kenkyū-buntansha) |
HAMADA Taizo Hiroshima University, Graduate School of Biomedical Sciences, Professor, 大学院・医歯薬学総合研究科, 教授 (50034244)
|
|---|
| Project Period (FY) |
2001 – 2002
|
| Keywords | Soft denture liner / Environmental endocrine disruptor / Viscoelasticity / Masticatory function / Plasticizer |
|---|
| Research Abstract |
Denture soft liners mare widely used in edentulous patient by means of specific viscoelastic properties. However, recently environmental endocrine disruptors (phthalic esters) which are included in some soft denture liners are social problem. The purpose of this study is development of functional soft denture liners without environmental endocrine disruptors. Influence of type of ester plasticizer, polymer, and monomer on viscoelastic properties, water absorption, solubility, and masticatory function are evaluated.
In 2001, relationship between dynamic viscoelastic properties of soft liners and masticatory function was studied. The shear storage modulus (G'), shear loss modulus (G") and loss tangent (tan δ) were determined for six materials using a dynamic viscoelastometer. Masticatory function of ten subjects was evaluated by measurements of maximum bite forces and chewing times and frequencies for two food-samples, and using visual analogue scales. The acrylic materials exhibited viscoelastic behavior, whilst the silicones exhibited elastic behavior. It was found that the use of materials with higher tan d and G' provides the most optimum masticatory function for patients requiring the provision of soft liners on their dentures. The linear dimensional changes with time of tissue conditioners using a traveling microscope and relationship between these changes and weight changes were evaluated. The absorption and solubility of these materials were also determined.
In 2002, relationship between plasticizer (dibutyl sebacate), and viscoelasticity and adhesion to denture base resins were studied. These results are planed to be presented in 81th General Session and Exhibition of the International Association of Dental Research.
|
