2005 Fiscal Year Final Research Report Summary
Sociomedical-informative study on establishment of supporting model of health behavior changes
| Project/Area Number |
14207017
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| Research Category |
Grant-in-Aid for Scientific Research (A)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Hygiene
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| Research Institution | Osaka University |
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Principal Investigator |
MORIMOTO Kanehisa Osaka University, Grad.Sch.of Med., Prof., 医学系研究科, 教授 (20143414)
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| Co-Investigator(Kenkyū-buntansha) |
NAKAYAMA Kunio Osaka University, Grad.Sch.of Med., Assist., 医学系研究科, 助手 (80346197)
TODA Masahiro Osaka University, Grad.Sch.of Med., Assist., 医学系研究科, 助手 (90362714)
LU Yuquan Osaka University, Grad.Sch.of Med., Assist., 医学系研究科, 助手 (90362722)
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| Project Period (FY) |
2002 – 2005
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| Keywords | Lifestyle / Natural killer cell activity / Chromosome aberration / Stress / Cortisol / Brain science / Aging / Preventive medicine |
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| Research Abstract |
The total environments to which individuals have been exposed throughout the lifestages from birth to the present time have been composing the individual and community lifestyles, or ways of daily living. Such lifestyles are known to determine the risks for development of cancers, circulatory diseases, and other chronic diseases. To establish new theory and practice programs for disease prevention and health promotion in the environmental medicine, we have quantitatively investigated correlations of lifestyle to comprehensive health potentials. The health potentials were assessed by both the ridit and multiphasic analysis of general health-check-up data, and the measurements of typical biomarkers such as lymphocyte chromosome alterations, natural-killer cell activities, and serum IgE levels.
The general health status was assessed by the ridit analysis of the incidence of abnormal values in blood-biochemistry, blood-pressure, and urine tests of multiphasic health check-ups. The general health was found to decrease with aging, but to vary a lot according to their lifestyles. For example, the mean level of somatic health of the persons having poor lifestyles in the 20's was about the same that of those with good lifestyles in the 40's. According to the results of follow-up of workers, the unhealthy workers were found to have had significantly higher risks for the developments of chronic diseases such as heart attack, liver disease, and diabetes.
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Research Products
(60 results)
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[Journal Article] Effects of alcohol on hemodynamic and cardiovascular reaction in different genotypes.2005
Author(s)
Obata, A, Morimoto, K., Sato, H., Takeshita, T, Kawaguchi, H., Koizumi, H., Maki, A.
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Journal Title
Psychiat.Res. 139
Pages: 65-72
Description
「研究成果報告書概要(欧文)」より
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[Journal Article] Reduction in salivary cortisol level by music therapy during colonoscopic examination.2005
Author(s)
Uedo, N., Ishikawa, H., Morimoto, K., Ishihara, R., Narahara, H., Akedo, I., Ioka, T., Kaji, I., Fukuda, S.
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Journal Title
Hepatogastroenterol. 51
Pages: 451-453
Description
「研究成果報告書概要(欧文)」より
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[Journal Article] Secretory IgA in Saliva and academic stress.2004
Author(s)
Otsuki, T., Sakaguchi, H., Hatayama, T., Takata, A., Hyodoh, F., Tsujita, S., Ueki, A., Morimoto, K.
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Journal Title
Int.J.Immunopath.Pharmacol. 17
Pages: 45-48
Description
「研究成果報告書概要(欧文)」より
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[Journal Article] The relationship of Atopy, smoking, and sensitization to Methyltetrahydrophthalic anhydride.2004
Author(s)
Yokota, K., Johyama, Y., Yamaguchi, K., Takeshita, T., Morimoto, K.
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Journal Title
Int.J.Immunopath.Pharmacol. 17
Pages: 83-89
Description
「研究成果報告書概要(欧文)」より
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[Journal Article] Role of Fas/Fas ligand-mediated apoptosis in murine contact hypersensitivity.2003
Author(s)
Xu BH, Bulfone-Paus S., Aoyama, K., Yu S., Haung PX, Morimoto, K., Matsushita, T., Takeuchi, T.
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Journal Title
Int.Immunopharmacol. 3
Pages: 927-938
Description
「研究成果報告書概要(欧文)」より
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[Journal Article] Helicobacter pylori-induced enlarged-fold gastritis is associated with increased mutagenicity of gastric juice, increased oxidative DNA damage, and an increased risk of gastric carcinoma.2003
Author(s)
Nishibayashi, H., Kanayama, S., Kiyohara, T., Yamamoto, K., Miyazaki, Y., Yasunaga, Y., Shinomura, Y., Takeshita, T., Takeuchi, T., Morimoto, K., Matsuzawa, Y.
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Journal Title
J.Gastroenterol.Hepathol. 18
Pages: 1384-1391
Description
「研究成果報告書概要(欧文)」より
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[Journal Article] Effects of Aldehyde Dehydrogenase Genotypes on Carotid Atherosclerosis.2003
Author(s)
Narita, M., Kitagawa, K., Nagai, Y., Hougaku, H., Hashimoto, H., Sakaguchi, M., Yang, X., Takeshita, T., Morimoto, K., Matsumoto, M., Hori, M.
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Journal Title
Ultrasound Med.Biol. 29
Pages: 1415-1419
Description
「研究成果報告書概要(欧文)」より
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[Journal Article] Association of ALDH2 genotypes and alcohol consumption with periodontitis.2003
Author(s)
Nishida, N., Tanaka, M., Hayashi, N., Nagata, H., Takeshita, T., Nakayama, K., Morimoto, K., Shizukuishi, S.
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Journal Title
J.Dent.Res. 83
Pages: 161-165
Description
「研究成果報告書概要(欧文)」より
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[Journal Article] Intramolecular epitope spreading among anti-caspase-8 autoantibodies in patients with silicosis, systemic sclerosis and systemic lupus erythematosus, as well as in healthy individuals.2002
Author(s)
Ueki, A., Isozaki, Y, Tomokuni, A., Hatayama, T, Ueki, H., Kusaka, M., Shiwa, M., Arikuni, H., Takeshita, T., Morimoto, K.
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Journal Title
Clin.Exp.Immunol. 129
Pages: 556-561
Description
「研究成果報告書概要(欧文)」より
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[Book] 現代医学と社会2005
Author(s)
森本兼曩
Total Pages
259
Publisher
朝倉書店
Description
「研究成果報告書概要(和文)」より
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