2004 Fiscal Year Final Research Report Summary
Imaging and image processing for integrated understanding of multi-modal medical images
| Project/Area Number |
14350215
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| Research Category |
Grant-in-Aid for Scientific Research (B)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Measurement engineering
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| Research Institution | Yamagata University |
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Principal Investigator |
AKATSUKA Takao Yamagata Univ., Faculty of Engineering, Professor, 工学部, 教授 (80091875)
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| Co-Investigator(Kenkyū-buntansha) |
TAMURA Yasutaka Yamagata Univ., Fac.of Engineering, Prof., 工学部, 教授 (40171904)
YUASA Testsuya Yamagata Univ., Fac.of Engineering, Assoc.Prof, 工学部, 助教授 (30240146)
HOSOYA Takaaki Yamagata Univ., Fac.of Medicine, Prof., 医学部, 教授 (50143102)
TAKEDA Tohoru Univ.of Tsukuba, Inst.of Clinical Med., Assistant Prof, 大学院・人間総合科学研究科, 講師 (10197311)
FUKAMI Tadanori Yamagata Univ., Fac.of Engineering, Res.Assoc., 工学部, 助手 (70333987)
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| Project Period (FY) |
2002 – 2004
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| Keywords | medical image / multi-modality / image fusion / image registration / integrated image understanding / SR imaging / SPECT / MRI / PET / MRI |
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| Research Abstract |
For advanced and protective medicine, it is an important study to establish reliable multi-modal image evaluation and to construct a supporting system for diagnosis corresponding to the physiological dynamics of organ or tissue. On this purpose, imaging and image processing techniques must be key-technologies to obtain both morphological and functional information and to improve each observation by using mutual information.
It is started to realize new CT imaging techniques for functional and morphological image. In synchrotron radiation imaging, we have succeeded to describe them simultaneously by using fluorescent and Compton scattering phenomena on the target organ with considerable effect of mutual information. In case of the combination with fluorescent X-ray CT and phase-contrast CT images, we can evaluate properly the situation of functional changes of organ. Trans-illumination optical CT is also developed and discussed to utilize attenuation coefficient and spectrum broadening of transmitted light to characterize target organ such as human finger joint.
For clinical evaluation of cardiac wall function, we have already developed an interactive 3D display system where functional information from SPECT are superposed on 3D morphological description from MRI, and succeeded to demonstrate the validity of integrated presentation. Here we have developed an automatic processing procedure for this purpose by using clear described organs near the target organ.
We have also developed several procedures in automatic 3D registration on image fusion for PET/MRI and SPECT/MRI images, and to get a few parameters for quantitative clinical evaluation. Further effort is now concentrated on tuning processing parameters corresponding individual target for clinical use.
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Research Products
(158 results)
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[Journal Article] In-vivo imaging of tracer element with fluorecent X-ray computed tomography2005
Author(s)
T.Takeda, J.Wu, Thet-Thet-Lwin, Y.Tsuchiya, N.Sunaguchi, T.Kuroe, T.Yuasa, K.Hyodo, F.A.Dilmanian, M.Minami, T.Akatsuka
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Journal Title
Proc.APCMBE, IFMBE Proceedings Vol.8
Pages: PA3-PA33
Description
「研究成果報告書概要(欧文)」より
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[Journal Article] Integrated imaging of mouse brain with fluorescent and phase-contrast X-ray CT2005
Author(s)
Wu J, Takeda T, Thet-Thet-Lwin, Tsuchiya Y, Sunaguchi N, Kuroe T, Yoneyama A, Yuasa T, Hyodo K, Hontani H, Minami M, Hirai Y, Akatsuka T
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Journal Title
Proc.APCMBE, IFMBE Proceedings Vol.8
Pages: PA3-PA37
Description
「研究成果報告書概要(欧文)」より
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[Journal Article] Development of high speed fluorescent X-ray micro-computed tomography2004
Author(s)
T.Takeda, Y.Tsuchiya, T.Kuroe, T.Zeniya, J.Wu, T.T.Lwin, T.Yashiro, T.Yuasa, K.Hyodo, K.Matsumura, F.A.Dilmanian, Y.Itai, T.Akatsuka
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Journal Title
Synchrotron Radiation Instrumentation CP705
Pages: 1320-1323
Description
「研究成果報告書概要(欧文)」より
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[Journal Article] Micro-phase-contrast x-ray computed tomography for basic biomedical study at Spring-82004
Author(s)
J.Wu, T.Takeda, T.T.Lwin, I.Koyama, A.Momose, Y.Hamaishi, A.Fujii, T.Kuroe, T.Yuasa, Y.Suzuki, T.Akatsuka
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Journal Title
Proc.of SPIE Vol.5535
Pages: 740-747
Description
「研究成果報告書概要(欧文)」より
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[Journal Article] Micro-phase-contrast X-ray computed tomography for basic biomedical study in SPring-8.2004
Author(s)
Wu J, Takeda T, Thet Thet Lwin, Koyama I, Momose A, Fujii A, Hamaishi Y, Kuroe T, Yuasa T, Suzuki Y, Akatsuka T
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Journal Title
Proceedings of SPIE Vol.5535
Pages: 740-747
Description
「研究成果報告書概要(欧文)」より
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[Journal Article] SR biomedical imaging with phase-contrast and fluorescent x-ray CT.[Invited Paper]2004
Author(s)
Takeda T, Wu J, Yoneyama A, Tsuchiya Y, Thet-Thet-Lwin, Hirai Y, Kuroe T, Yuasa T, Hyodo K, Dilmanian FA, Akatsuka T
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Journal Title
Proceedings of SPIE Vol.5535
Pages: 380-391
Description
「研究成果報告書概要(欧文)」より
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[Journal Article] Prototype System of Laser Transillumination Computed Tomography for Early Diagnosis of Rheumatoid Arthritis2003
Author(s)
Y.Sasaki, S.Tanosaki, M.Takagi, A.Ishikawa, J.Suzuki, R.Emori, H.Inage, T.Yuasa, H.Taniguchi, B.Devaraj, T.Akatsuka
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Journal Title
Proc.of SPIE, Fibers and Sensors for Medical Applications III Vol.4957
Pages: 183-190
Description
「研究成果報告書概要(欧文)」より
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[Journal Article] Transillumination laser computed tomography system with fiber-optic-based coherent detection imaging method-High spatial-resolution and quantitative tomographic imaging of high scatter object-2003
Author(s)
Y.Sasaki, J.Suzuki, H.Inage, R.Emori, S.Tanosaki, T.Yuasa, M.Takagi, A.Ishikawa, H.Taniguchi, B.Devaraj, T.Akatsuka
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Journal Title
Optical Review Vol.10,No.5
Pages: 462-465
Description
「研究成果報告書概要(欧文)」より
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[Journal Article] In vivo laser tomographic imaging of mouse leg by coherent detection imaging method2003
Author(s)
S.Tanosaki, Y.Sasaki, M.Takagi, A.Ishikawa, H.Inage, R.Emori, T.J.Suzuki, Yuasa, H.Taniguchi, B.Devaraj, T.Akatsuka
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Journal Title
Optical Review Vol.10,No.5
Pages: 447-451
Description
「研究成果報告書概要(欧文)」より
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[Journal Article] Finger Joint Imaging by Laser Transillumination Computed Tomography Based on Coherent Detection Imaging Method2003
Author(s)
S.Tanosaki, Y.Sasaki, M.Takagi, A.Ishikawa, J.Suzuki, R.Emori, H.Inage, T.Yuasa, H.Taniguchi, B.Devaraj, T.Akatsuka
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Journal Title
Proc.of SPIE, Optical Tomography and Spectroscopy of Tissue V Vol.4955
Pages: 615-623
Description
「研究成果報告書概要(欧文)」より
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[Journal Article] Biomedical Imaging with Fluorescent and Interferometric Phase Contrast Method2002
Author(s)
T.Takeda, A.Yoneyama, Jin Wu, T.Zeniya, Y.Tsuchiya, Thet-Thet-Lwin, DV Rao, S.Matsushita, T.Yuasa, T.Yashiro, Y.Aiyoshi, K.Hyodo, K.Hirano, A.Momose, T.Akatsuka, Y.Itai
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Journal Title
Proc.of the 6th World Multi-conference on Systemics, Cybernetics, and Informatics[Best Paper Award] (CD-ROM)
Description
「研究成果報告書概要(欧文)」より
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[Journal Article] Medical Imaging by Fluorescent X-Ray : Its Preliminary Clinical Evaluation2002
Author(s)
T.Takeda, T.Zeniya, Jin Wu, Q.Yu, Thet-Tet-Lwin, Y.Tsuchiya, DV Rao, T.Yuasa, A.Dilmanian, Y.Itai, T.Akatsuka
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Journal Title
Proc.of SPIE, Development in X-Ray Tomography III vol.4503
Pages: 299-309
Description
「研究成果報告書概要(欧文)」より
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[Journal Article] In Vivo Laser Tomograhpic Imaging of Mouse Leg with Coherent Detection Imaging Method2002
Author(s)
S.Tanosaki, M.Takagi, Y.Sasaki, A.Ishikawa, H.Inage, R.Emori, J.Suzuki, T.Yuasa, H.Taniguchi, B.Devaraj, T.Akatsuka
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Journal Title
Proc.of Asian Symposium on Biomedical Optics and Photomedicine (BOPM)
Pages: 194-195
Description
「研究成果報告書概要(欧文)」より
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