2003 Fiscal Year Final Research Report Summary

Architecture of lung parenchyma and its implication to radiologic interpretation

Research Project

Project/Area Number	14570846
Research Category	Grant-in-Aid for Scientific Research (C)
Allocation Type	Single-year Grants
Section	一般
Research Field	Radiation science
Research Institution	Faculty of Medical Sciences, University of Fukui
Principal Investigator	ITOH Harumi University of Fukui, Faculty of Medical Sciences, Professor, 医学部, 教授 (40026943)
Project Period (FY)	2002 – 2003
Keywords	lung parenchyma / image diagnosis / lung specimen / alveolar duct / alveolar dome / diffuse lung disease
Research Abstract	The purpose of the study was to analyse architecture of lung parenchyma in order to promote further understanding of disease process extending in the lung. Stereomicroscopic, histologic and radiologic examinations were done in inflated and fixed lung specimens. The key structure of lung parenchyma was double sheets of alveoli separating two adjacent alveolar ducts. In this case, alveolar dome is hold in common between the double sheets. Pulmonary vessels were situated among the alveolar ducts. Adenocarcinoma is disease where cancer extends continuously along the double alveolar sheets. Pulmonary tuberculosis is typical in which alveolar ducts are filled by exdudates. Sarcoisosis is characterized by guranolomas formed along pulmonary vessels. These diseases are well understood with new knowledges about lung parenchyma gotten by this study. This study provided morphologic bases of evaluating normal and abnormal X-ray images.

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