2004 Fiscal Year Final Research Report Summary
PROSPECTIVE STUDY OF PERSONALTY, STRESS AND CANCER SURVIVAL
| Project/Area Number |
15390194
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| Research Category |
Grant-in-Aid for Scientific Research (B)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Public health/Health science
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| Research Institution | TOHOKU UNIVERSITY |
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Principal Investigator |
TSUBONO Yoshitaka TOHOKU UNIVERSITY, SCHOOL OF LAW, PROFESSOR, 大学院・法学研究科, 教授 (00250746)
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| Co-Investigator(Kenkyū-buntansha) |
FUKUDO Shin TOHOKU UNIVERSITY, SCHOOL OF MEDICINE, PROFESSOR, 大学院・医学系研究科, 教授 (80199249)
HOSOKAWA Toru TOHOKU UNIVERSITY, SCHOOL OF EDUCATION, PROFESSOR, 大学院・教育学研究科, 教授 (60091740)
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| Project Period (FY) |
2003 – 2004
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| Keywords | PERSONALITY / CHARACTER / COHORT STUDY / EPIDEMIOLOGY / CANCER / CANCER REGISTRY / SURVIVAL |
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| Research Abstract |
It has long been hypothesized that personality and stress play a role in cancer outcome, and in this study we tested this hypothesis in a population-based prospective cohort study in Japan. In July 1990, 41,442 residents of Japan completed a short form of the Eysenck Personality Questionnaire-Revised and a questionnaire on stress and various health habits, and between January 1993 and December 1997, 890 incident cases of cancer were identified among them. These 890 cases were followed up until March 2001, and a total of 356 deaths from all causes was identified among them. Cox proportional-hazards regression was used to estimate the hazard ratio (HR) of death according to four score levels on each of four personality subscales (extraversion, neuroticism, psychoticism, and lie), with adjustment for potential confounding factors. Multivariable HRs of deaths from all causes for individuals in the highest score level on each personality subscale compared with those at the lowest level were 1.0 for extraversion (95% CI=0.8-1.4 ; Trend P=0.73), 1.1 for neuroticism (0.8-1.6 ; Trend P=0.24), 1.2 for psychoticism (0.9-1.6 ; Trend P=0.29), and 1.0 for lie (0.7-1.5 ; Trend P=0.90). Stress was not associated with cancer survival. The data obtained in this population-based prospective cohort study in Japan do not support the hypothesis that personality or stress is associated with cancer survival.
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