2004 Fiscal Year Final Research Report Summary
Mechanism of information processing in the posterior cingulate cortex-hippocampal system
| Project/Area Number |
15500283
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Neurophysiology and muscle physiology
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| Research Institution | TOYAMA MEDICAL AND PHARMACEUTICAL UNIVERSITY |
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Principal Investigator |
TABUCHI Eiichi Toyama Medical and Pharmaceutical University, System Emotional Science, Associate Professor, 大学院・医学系研究科, 助教授 (70272911)
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| Co-Investigator(Kenkyū-buntansha) |
UMENO Katsumi Toyama Medical and Pharmaceutical University, System Emotional Science, Assistant Professor, 大学院・医学系研究科, 助手 (90086596)
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| Project Period (FY) |
2003 – 2004
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| Keywords | Limbic system / Posterior cingulate cortex / Neural network / Hippocampus / Neuron / Cross-correlation / Behavior / Reward |
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| Research Abstract |
We found that neurons in the posterior cingulate cortex respond not to sensory stimuli but to motor action for a certain reward acquisition. Also, it is found that the hippocampal regions having reciprocal connection with the posterior cingulate cortex alter their responses in accord with place and condition. In the present study, to clarify how the context dependent hippocampal information converted into the posterior cingulate cortex which acts on motor evaluation, we recorded multiple single neuronal activities simultaneously from the posterior cingulate cortex and hippocampus in a sensory-reward association learning task. In this task, a water deprived rat received water or an intracranial self-stimulation (ICSS) (both reward), when the rat pressed a lever at a lit wall in an octagonal arena. The arena was equipped with 4 levers where one of 4 different rewards (small or large volume of water, weak or strong ICSS) was delivered. Then, we analyzed the neuronal activities in behavioral correlates, and the neuronal connectivity between the 2 brain regions using the cross-correlation method.
We found significant cross-correlation peaks in some pairs between the posterior cingulate cortex and hippocampal neurons during drinking in a specific position. The time difference of their discharges was 10 ms. These findings suggest that the connection from the hippocampus to the posterior cingulate cortex may convey integrated information among space, reward, and motion.
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Research Products
(20 results)
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[Journal Article] Neural correlates to action and rewards in the rat posterior cingulate cortex.2005
Author(s)
Tabuchi, E., Furusawa, A.A., Hori, E., Umeno, K., Ono, T., Nishijo, H.
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Journal Title
Description
「研究成果報告書概要(欧文)」より
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[Journal Article] Autonomic responses during inhalation of natural fragrance "Cedrol" in humans.2003
Author(s)
Dayawansa S., Umeno K., Takakura M., Hori E., Tabuchi E., Nagashima Y., Oosu H., Yada Y., Suzuki T., Ono T., Nishijo H.
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Journal Title
Autonomic Neuroscience-Basic & Clinical 108
Pages: 79-86
Description
「研究成果報告書概要(和文)」より
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[Journal Article] Spatial and behavioral correlates in nucleus accumbens neurons in zones receiving hippocampal or prefrontal cortical inputs.2003
Author(s)
Wiener S.I., Shibata R., Tabuchi E., Trullier O., Albertin S.V., Murder A.B
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Journal Title
Cognition and Emotion in the Brain (by Ono T., Matsumoto G., Llinas R.R., Berthoz A., Norgren R., Nishijo H., Tamura R.(Eds.))(Elsevier, Amsterdam)
Pages: 275-292
Description
「研究成果報告書概要(欧文)」より
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[Journal Article] Role of the monkey amygdala in social cognition.2003
Author(s)
Nishijo H., Hori E., Tazumi T., Eifuku S., Umeno K., Tabuchi E., Ono T.
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Journal Title
Cognition and Emotion in the Brain (by Ono T., Matsumoto G., Llinas R.R., Berthoz A., Norgren R., Nishijo H., Tamura R.(Eds.))(Elsevier, Amsterdam)
Pages: 295-310
Description
「研究成果報告書概要(欧文)」より
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[Journal Article] Representation of place by monkey hippocampal neurons in real and virtual translocation.2003
Author(s)
Hori, E., Tabuchi, E., Matsumura, N., Tamura, R., Eifuku, S., Endo, S., Nishijo, H., Ono, T.
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Journal Title
Hippocampus 13
Pages: 148-154
Description
「研究成果報告書概要(欧文)」より
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[Journal Article] Differential activation in the medial temporal lobe during a sound-sequence discrimination task across age in human subjects.2003
Author(s)
Takakura, H., Umeno, K., Tabuchi, E., Hori, E., Miyamoto, K., Aso, S., Watanabe, Y., Ono, T., Nishijo, H.
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Journal Title
Neuroscience 119
Pages: 517-532
Description
「研究成果報告書概要(欧文)」より
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[Journal Article] Gamma-band EEGs predict autonomic responses during mental arithmetic.2003
Author(s)
Umeno, K., Hori, E., Tabuchi, E., Takakura, H., Miyamoto, K., Ono, T., Nishijo, H.
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Journal Title
Neuroreport 14
Pages: 477-480
Description
「研究成果報告書概要(欧文)」より
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[Book] Role of the monkey amygdala in social cognition. In : Cognition and Emotion in the Brain.(Ono T., Matsumoto G., Llinas R.R., Berthoz A., Norgren R., Nishijo H., Tamura R. (Eds.))2003
Author(s)
Nishijo H., Hori E., Tazumi T., Eifuku S., Umeno K., Tabuchi E., Ono T.
Total Pages
295-310
Publisher
Amsterdam, Elsevier
Description
「研究成果報告書概要(和文)」より
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[Book] Spatial and behavioral correlates in nucleus accumbens neurons in zones receiving hippocampal or prefrontal cortical inputs. In : Cognition and Emotion in the Brain.(Ono T., Matsumoto G., Llinas R.R., Berthoz A., Norgren R., Nishijo H., Tamura R. (Eds.))2003
Author(s)
Wiener S.I., Shibata R., Tabuchi E., Trullier O., Albertin S.V., Mulder A.B.
Total Pages
275-292
Publisher
Amsterdam, Elsevier
Description
「研究成果報告書概要(和文)」より
