Development of porous metallic biomaterials with high strength, low elastic modulus and excellent biocompatibility

2017 Fiscal Year Final Research Report

• Project/Area Number: 15H03016
• Research Category: Grant-in-Aid for Scientific Research (B)
• Allocation Type: Single-year Grants
• Section: 一般
• Research Field: Biomedical engineering/Biomaterial science and engineering
• Research Institution: Tohoku University
• Principal Investigator: Xie Guoqiang 東北大学, 多元物質科学研究所, 産学官連携研究員 (50422134)
• Co-Investigator(Kenkyū-buntansha): 金高 弘恭 東北大学, 歯学研究科, 准教授 (50292222)
• Project Period (FY): 2015-04-01 – 2018-03-31
• Keywords: 金属ガラス / ポーラス材料 / 放電プラズマ焼結法 / 生体・医療材料 / 微細構造 / 強度 / ヤング率 / 気孔率

Outline of Final Research Achievements

Porous Ni- and Be-free Ti-based bulk metallic glass (BMG) with a diameter exceeding 15 mm was developed by spark plasma sintering (SPS) the mixture of gas-atomized Ti-based glassy alloy powder and solid salt (NaCl) powder, followed by leaching treatment to eliminate the salt phase. The developed porous Ti-based BMG alloy exhibited high yield strength, simultaneously matched the Young’s modulus of natural bone, and demonstrated high corrosion resistance and excellent biocompatibility. These results suggest that porous Ti-based BMGs produced by the SPS process open an advanced alternative for clinical applications under load-bearing conditions such as surgical implants.

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