Design of Surface Separation Media for Selective Collection of Drugs and Application to Hospital Wastewater Treatment

2017 Fiscal Year Final Research Report

• Project/Area Number: 15H03842
• Research Category: Grant-in-Aid for Scientific Research (B)
• Allocation Type: Single-year Grants
• Section: 一般
• Research Field: Green/Environmental chemistry
• Research Institution: Kitami Institute of Technology
• Principal Investigator: Saitoh Tohru 北見工業大学, 工学部, 教授 (40186945)
• Co-Investigator(Kenkyū-buntansha): 上原 伸夫 宇都宮大学, 工学(系)研究科(研究院), 教授 (50203469) ; 高貝 慶隆 福島大学, 共生システム理工学類, 准教授 (70399773) ; 前田 貴史 北見工業大学, 工学部, 特任助教 (80758227)
• Project Period (FY): 2015-04-01 – 2018-03-31
• Keywords: 医療排水処理 / 薬物 / 迅速除去 / オルガノクレー / フローテーション / 界面活性剤 / 環境負荷低減

Outline of Final Research Achievements

Air/water and solid/water interfaces were designed for highly efficient removal of pharmaceuticals from hospital wastewaters.
A coagulation-flotation method using sodium dodecyl sulfate, poly(allylamine hydrochloride), and Al(III) ions was useful for eliminating tetracycline and fluoroquinolone antibiotics. The antibiotics were sorbed on surfactant-modified air/water interfaces as the hydrophobic ion-pair of their Al(III) chelates with dodecyl sulfate ions. The method was also applicable to the removal of different acidic and basic drugs.
On the other hand, β-lactam antibiotics in water were rapidly removed and degraded by using dialkylated cationic surfactant-modified organoclay. At 25°C and pH 7, penicillin G (m/z = 335) nearly completely (>98%) degraded into penicilloic acid (m/z = 353) missing β-lactam ring within 2 h. The applicability to wastewater treatment was successfully demonstrated by using secondary effluents and synthesized hospital wastewaters.

Free Research Field

分析化学