2017 Fiscal Year Final Research Report
Experimental demonstration and understanding of host-parasite coevolution
| Project/Area Number |
15H04407
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| Research Category |
Grant-in-Aid for Scientific Research (B)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Evolutionary biology
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| Research Institution | Osaka University |
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Principal Investigator |
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| Project Period (FY) |
2015-04-01 – 2018-03-31
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| Keywords | 進化 / 軍拡競争 / RNA / 寄生体 |
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| Outline of Final Research Achievements |
In this project, we aimed to understand possible evolutionary processed between hosts and parasites by constructing a simplified experimental model using self-replicating RNAs. We succeeded the construction and performed a long-term replication experiment of a host RNA with a parasitic RNA. In the replication process, we found that the host RNA evolved a resistance to the parasitic RNA by changing the encoded replicase function, and then the parasite adapt to the changed host RNA by introducing mutations. These results indicate that the host and parasitic RNAs performed an evolutionary arms-race, which can be a useful experimental model to understand coevelutionary process between hosts and parasites.
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| Free Research Field |
進化生物学
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