2017 Fiscal Year Final Research Report
The surgical lymphatic regeneration for improving the prognosis of melanoma
| Project/Area Number |
15H05001
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| Research Category |
Grant-in-Aid for Scientific Research (B)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Plastic surgery
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| Research Institution | Hokkaido University |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
林 利彦 北海道大学, 歯学研究院, 准教授 (00432146)
舟山 恵美 北海道大学, 医学研究院, 講師 (10533630)
山本 有平 北海道大学, 医学研究院, 教授 (70271674)
小山 明彦 北海道大学, 大学病院, 講師 (70374486)
村尾 尚規 北海道大学, 大学病院, 助教 (90706558)
七戸 龍司 北海道大学, 大学病院, 医員 (30640346)
関堂 充 筑波大学, 医学医療系, 教授 (40372255)
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| Project Period (FY) |
2015-04-01 – 2018-03-31
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| Keywords | リンパ系再構築 / リンパ節移植 / 循環系 / 免疫系 / 回復 |
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| Outline of Final Research Achievements |
Recently, as a relatively new physiologic surgical treatment of impairment of local lymphatic system, lymph node transplantation was introduced and applied. However, the reports supporting the utility of the lymph node transplantation are limited.
Here, the authors demonstrated that a transplanted LN served as a tumor-draining LN and exerted an immune-mediated antitumor effect. Following local tumor control by surgical resection, an additional lymph node transplant might be practical for preventing lymphedema and reduced immunity.
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| Free Research Field |
形成外科
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