Exploration of streptococcal factors related with onset of bacteremia and systemic dissemination

2017 Fiscal Year Final Research Report

• Project/Area Number: 15H05012
• Research Category: Grant-in-Aid for Scientific Research (B)
• Allocation Type: Single-year Grants
• Section: 一般
• Research Field: Morphological basic dentistry
• Research Institution: Osaka University
• Principal Investigator: KAWABATA SHIGETADA 大阪大学, 歯学研究科, 教授 (50273694)
• Co-Investigator(Kenkyū-buntansha): 山口 雅也 大阪大学, 歯学研究科, 助教 (00714536) ; 住友 倫子 大阪大学, 歯学研究科, 講師 (50423421) ; 中田 匡宣 大阪大学, 歯学研究科, 准教授 (90444497)
• Project Period (FY): 2015-04-01 – 2018-03-31
• Keywords: レンサ球菌

Outline of Final Research Achievements

During the onset of invasive streptococcal diseases, bacteria systemically disseminate via the bloodstream. The exact mechanism by which pathogenic streptococci evade host immunity and disseminate to the bloodstream remains elusive. In this study, we revealed factors of pathogenic streptococci, including Streptococcus pneumoniae, Streptococcus pyogenes, and oral streptococci, involved in tissue invasion, immune evasion, and bacterial survival in the blood stream.

Free Research Field

細菌学