Epidemiological study on rotavirus diarrhea and a study on the mode of trasmisson

2017 Fiscal Year Final Research Report

• Project/Area Number: 15H05286
• Research Category: Grant-in-Aid for Scientific Research (B)
• Allocation Type: Single-year Grants
• Section: 海外学術
• Research Field: Hygiene and public health
• Research Institution: Nagasaki University
• Principal Investigator: ICHINOSE Yoshio 長崎大学, 熱帯医学研究所, 教授 (70176296)
• Co-Investigator(Kenkyū-buntansha): 長谷川 慎 長浜バイオ大学, バイオサイエンス学部, 教授 (10367899)
• Research Collaborator: Ernest Apondi Wandera ; Mohamed Monir Shah ; Erick Odoyo
• Project Period (FY): 2015-04-01 – 2018-03-31
• Keywords: ロタウイルス / ジェノタイピング / ワクチン効果 / 感染モード / ケニア

Outline of Final Research Achievements

We have performed the epidemiological study of rotavirus diarrhea in Kenya in relation to countrywide introduction of a rotavirus vaccine (Rotarix vaccine) as well as the its impact to reduce the infections and the study of mode of transmission of rotavirus particles. Rotavirus vaccine reduced 50% of Rotavirus diarrhea in Kenya and a genotype G2P4 increase as a dominant genotype. We also could identify rotavirus particles out of 6.1% of the air samples collected by a metal mesh device by semi-nested PCR. It is suggested that rotavirus particles can spread via air in addition to the transmission via water and food.

Free Research Field

細菌学、熱帯医学