Analysis of multi time-scale dynamics in mechanobiological stimulation by impulsive force

2016 Fiscal Year Final Research Report

• Project/Area Number: 15H05352
• Research Category: Grant-in-Aid for Young Scientists (A)
• Allocation Type: Single-year Grants
• Research Field: Biomedical engineering/Biomaterial science and engineering
• Research Institution: The University of Tokyo
• Principal Investigator: Nakagawa Keiichi 東京大学, 大学院工学系研究科(工学部), 助教 (00737926)
• Project Period (FY): 2015-04-01 – 2017-03-31
• Keywords: メカノバイオロジー / メカニカルストレス / 撃力 / レーザー / カルシウムイメージング

Outline of Final Research Achievements

In recent years, studies that clarify the mechanical action on the living body and aim at understanding diseases and applying them to medical treatment are actively conducted. In this study, we developed an impulsive force loading system to investigate how the instantaneous mechanical stimulus affects cells. Cells are given nanometer and microsecond scale displacement by a cantilever accelerated by nanosecond laser. We also acheved observation of a cell response with calcium imaging.

Free Research Field

医用工学，光工学，精密工学