2017 Fiscal Year Final Research Report
In vivo imaging of synaptic plasticity
| Project/Area Number |
15H05571
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| Research Category |
Grant-in-Aid for Young Scientists (A)
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| Allocation Type | Single-year Grants |
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| Research Field |
Neurophysiology / General neuroscience
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| Research Institution | Niigata University |
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Principal Investigator |
Matsui Hideaki 新潟大学, 研究推進機構, 准教授 (60710853)
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| Project Period (FY) |
2015-04-01 – 2018-03-31
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| Keywords | シナプス可塑性 |
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| Outline of Final Research Achievements |
In this study, we aimed to visualize AMPA receptor specifically at the post synaptic membrane and to observe and monitor the plastic and dynamic changes of synaptic functions. In primary neurons, our indicator successfully enables visualization of synaptic functions during chemical LTP or LTD. We have continued to utilize this indicator for hippocampal slice and zebrafish in vivo.
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| Free Research Field |
神経科学
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