2019 Fiscal Year Final Research Report
Hierarchal Control of Carbon Cluster Organization and Their Function
| Project/Area Number |
15H05754
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| Research Category |
Grant-in-Aid for Scientific Research (S)
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| Allocation Type | Single-year Grants |
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| Research Field |
Organic chemistry
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| Research Institution | The University of Tokyo |
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Principal Investigator |
Nakamura Eiichi 東京大学, 大学院理学系研究科(理学部), 特任教授 (00134809)
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| Co-Investigator(Kenkyū-buntansha) |
野入 英世 東京大学, 医学部附属病院, 特任研究員 (00301820)
原野 幸治 東京大学, 総括プロジェクト機構, 特任准教授 (70451515)
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| Project Period (FY) |
2015-05-29 – 2020-03-31
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| Keywords | π電子系 / フラーレン / 分子ワイヤ / 有機レーザー / 非晶質粒子 |
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| Outline of Final Research Achievements |
Structure determination, design/synthesis of molecules, and space temporal control of molecular events represent the modern paradigm of organic chemistry. This project has focused on the hierarchal control of the solution and solid-state chemistry including time evolution of the structures of molecules and molecular assemblies. In doing so, we focused on the diverse functional activities of carbon cluster compounds possessing pi-conjugated systems, deepened our understanding of space temporal control, and developed biomedical and industrial applications. We have synthesized conical fullerene amphiphiles, and applied them for solubilization of nanoparticles, and for delivery of siRNA to kidney through a blood stream. We discovered that dissolution of tetrabenzoporphyrin in an organic acid results in precipitation of entangle fibers, a molecular wire showing a ON/OFF switching ratio of 2700.
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| Free Research Field |
物理有機化学、有機合成化学、有機エレクトロニクス
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| Academic Significance and Societal Importance of the Research Achievements |
本研究は、分子設計と合成というゼロ次元の有機化学を基盤に、液相、固相、中間相での単一または複数種類の分子や粒子の３次元制御により、物性・デバイス機能、生物活性の分野に展開した。フラーレン、ポルフィリン、架橋共役系などの活性炭素クラスター化合物群を用いて、化学、医学、電子電気工学、顕微鏡科学にわたる広い境界領域分野を包含する研究を遂行する中で、日本および世界の未来を担う研究者、教育者を育成できた。
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