2017 Fiscal Year Final Research Report
Exploring the mechanism of gamma-oscillation alterations in early stages of schizophrenia
| Project/Area Number |
15H06166
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| Research Category |
Grant-in-Aid for Research Activity Start-up
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| Allocation Type | Single-year Grants |
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| Research Field |
Psychiatric science
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| Research Institution | The University of Tokyo |
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Principal Investigator |
Tada Mariko 東京大学, 医学部附属病院, 助教 (70758193)
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| Project Period (FY) |
2015-08-28 – 2018-03-31
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| Keywords | 統合失調症 / 脳波 / ガンマオシレーション |
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| Outline of Final Research Achievements |
Ultra-high-risk (UHR) individuals, patients with recent-onset schizophrenia (ROS), and healthy controls(HC), were recruited. Spontaneous power of gamma oscillations and the auditory steady-state response (ASSR) were calculated by electroencephalography during 40-Hz auditory click trains.The 40-Hz ASSR was reduced in both the UHR and ROS groups compared to that in HC. Spontaneous power of gamma oscillations showed a increase in ROS. The 40Hz-ASSRs were correlated with spontaneous power of gamma oscillations in each groups.
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| Free Research Field |
精神医学
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