C-H bond functionalizations of carboxylic acids by electron deficient CpE complexes

2016 Fiscal Year Final Research Report

• Project/Area Number: 15H06201
• Research Category: Grant-in-Aid for Research Activity Start-up
• Allocation Type: Single-year Grants
• Research Field: Organic chemistry
• Research Institution: Tokyo Institute of Technology
• Principal Investigator: Shibata Yu 東京工業大学, 物質理工学院, 助教 (30754494)
• Project Period (FY): 2015-08-28 – 2017-03-31
• Keywords: ロジウム / シクロペンタジエニル錯体 / C-H結合官能基化 / カルボン酸 / アルキン / イソクマリン / ナフタレン

Outline of Final Research Achievements

We developed that CpERh complex catalyzes various catalytic reactions, (1) oxidative [4+2] annulation of benzoic and acrylic acids with alkynes leading to isocoumarins and pyrones, (2) oxidative [2+2+2] annulation of benzoic acid with two alkynes via C-H bond cleavage and decarboxylation at room temperature under O2 leading to naphthalenes.

Free Research Field

有機金属化学・有機合成化学