Patterned Naofibers for cell culture by plasma treatment

2016 Fiscal Year Final Research Report

• Project/Area Number: 15H06586
• Research Category: Grant-in-Aid for Research Activity Start-up
• Allocation Type: Single-year Grants
• Research Field: Materials/Mechanics of materials
• Research Institution: Keio University
• Principal Investigator: Maeda Tomoki 慶應義塾大学, 理工学部(矢上), 助教 (00754730)
• Project Period (FY): 2015-08-28 – 2017-03-31
• Keywords: ナノファイバ / エレクトロスピニング法 / パターニング / 表面改質 / プラズマ処理

Outline of Final Research Achievements

In this study, the patterning method of electrospun nanofibers by plasma treatment was developed. Additionally, the cell culture on the patterned nanofibers was examined.
The PDMS surface was partially modified by using a mask during the plasma treatment. Then, the nanofibers were spun using the treated PDMS as a collector. As a result, the patterned nanofibers were obtained on the PDMS substrate. By adjusting the condition of plasma treatment and electrospinning, the patterned area became clearer. Furthermore, cells were cultured on the patterned nanofibers. As a result, the cell proliferation was enhanced on the patterned nanofibers as compared to the untreated surface.

Free Research Field

ポリマ材料