Analysis of a novel X-chromosomal short tandem repeat marker

2016 Fiscal Year Final Research Report

• Project/Area Number: 15H06632
• Research Category: Grant-in-Aid for Research Activity Start-up
• Allocation Type: Single-year Grants
• Research Field: Legal medicine
• Research Institution: Jikei University School of Medicine
• Principal Investigator: Nishi Takeki 東京慈恵会医科大学, 医学部, 助教 (70759472)
• Project Period (FY): 2015-08-28 – 2017-03-31
• Keywords: DNA多型 / X染色体 / STR / マイクロサテライト / 個人識別 / 血縁鑑定

Outline of Final Research Achievements

In this study, we identified novel tetranucleotide STR loci located in the X chromosome, which is the basis of X-STR research. The major findings of the study are summarized in the following.
1) Two novel tetranucleotides X-chromosomal short tandem repeats (X-STRs) in Xq28 region, 2) Four novel X-STRs within 71 kb of the Xp22.3 region, 3) Detection of a novel Pentanucleotide X-STRs in Xp22.3, 4) Three novel X-STR within a 90 kb region of the Xp22.3 region. These STRs are useful as DNA testing for forensic genetics.

Free Research Field

法医学