Impact evaluation of magnetic fields toward a target chemotherapy

2017 Fiscal Year Final Research Report

• Project/Area Number: 15K01328
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Multi-year Fund
• Section: 一般
• Research Field: Medical systems
• Research Institution: Kanazawa University
• Principal Investigator: Kakikawa Makiko 金沢大学, 電子情報学系, 准教授 (10359713)
• Co-Investigator(Kenkyū-buntansha): 山田 外史 金沢大学, 環日本海域環境研究センター, 連携研究員 (80019786)
• Project Period (FY): 2015-04-01 – 2018-03-31
• Keywords: 交流磁場 / がん細胞 / 薬剤作用

Outline of Final Research Achievements

We have constructed a magnetic fields exposure system for long-term experiments with human cells, and investigated the time dependence of magnetic fields exposure influence on drug potency. The results indicated that the potency of anticancer drug, cisplatin to human lung cancer cells was increased significantly by exposure to magnetic fields for 0.5 ~4 h, not for 24 h or more. Furthermore, our results suggested that the magnetic fields enhance the potency of anticancer drugs to not only lung cancer cells but also human hepatoma cells.

Free Research Field

生体工学