Measurement of neural connectivity at rest and during tasks by magnetoencephalography system

2017 Fiscal Year Final Research Report

• Project/Area Number: 15K09349
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Multi-year Fund
• Section: 一般
• Research Field: Neurology
• Research Institution: Nagoya University
• Principal Investigator: Hoshiyama Minoru 名古屋大学, 脳とこころの研究センター, 教授 (30270482)
• Project Period (FY): 2015-04-01 – 2018-03-31
• Keywords: 脳磁図 / 誘発脳反応 / 皮質内接続 / 安静時脳活動

Outline of Final Research Achievements

Resting and task-related magnetic cortical fields were measured by a magnetoencephalographic system (MEG), and inter-cortical connectivity was analyzed in physiological and pathological conditions. Change in neural connectivity during somatosensory, auditory, and motor tasks were calculated using latest methods, dipole distribution and coherence/correlation analyses, in healthy subjects. Pathological neural connectivity was investigated in patients with peripheral neuropathy, such as median nerve neuropathy at the wrist, and in patients with central nervous system. Parkinson’s disease. Present series of study resulted in 11 papers published in international journals. We believe that methods for analyzing inter-cortical connectivity during tasks and at rest have been established during our studies. Our methods could be applied to analysis using clinical electroencephalography recording. Application to clinical examination might be possible.

Free Research Field

臨床神経生理学