2017 Fiscal Year Final Research Report
Novel regulatory mechanism of B-cell lymphoma
| Project/Area Number |
15K09491
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Hematology
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| Research Institution | Aichi Medical University |
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Principal Investigator |
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| Co-Investigator(Renkei-kenkyūsha) |
Odkhuu Erdenezaya 愛知医科大学, 医学部, 助教 (40737681)
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| Project Period (FY) |
2015-04-01 – 2018-03-31
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| Keywords | MD-1 / RP105 / 脂質受容体 / S1P |
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| Outline of Final Research Achievements |
As a new control structure of B cell lymphoma, B-cell activated control by serum protein MD-1 was suggested. Because MD-1 is a lipid binding molecule and it also associates with RP105 inducing B-cell activation, lipid combination and the connection with the B-cell activation are thought about. Further analysis is necessary how the B cell lymphoma tendency is gained in the MD-1 deleted SLE model mouse by the B-cell activation reinforcement through Lipid and the receptor.
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| Free Research Field |
免疫学
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