Evaluation of perioperative obstructive sleep apnea in patient with dentofacial deformity

2017 Fiscal Year Final Research Report

• Project/Area Number: 15K11310
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Multi-year Fund
• Section: 一般
• Research Field: Surgical dentistry
• Research Institution: Kanazawa University
• Principal Investigator: OOI Kazuhiro 金沢大学, 附属病院, 講師 (90451450)
• Co-Investigator(Kenkyū-buntansha): 中村 博幸 金沢大学, 医学系, 准教授 (30542253)
• Project Period (FY): 2015-04-01 – 2018-03-31
• Keywords: 顎変形症 / 気道通気状態 / 睡眠呼吸障害

Outline of Final Research Achievements

Polysomnography was performed before orthographic surgery and sleep state were measured using peripheral arterial tonometry over night during 7 nights after surgery in general anesthesia. Apnea hypopnea index (AHI), lowest arterial oxgen saturation (LoSpO2) and sleep state were measured. AHI: 0.4 ( 0-12.1) /h, LoSpO2 : 92 (85-95)％, REM 20.1 (0-34.1)％, NREM 79.9 (65.9-100 ) ％,.One patient was diagnosed mild OSA. AHI during REM 1.8 (0-21) was higher than AHI during NREM 0.2 (0-9.7). The perioperative REM sleep was low until the 3 days after surgery and increased on the 4 days after surgery. pAHI increased from 3days after surgery, the highest in 4 cases on 7days after surgery, SPO 2 was the lowest in 3 cases on 4days after surgery and 5 peoples on 7days after surgery. The perioperative pAHI ( 9.2 (2.7-26.3)) is increase according to high BMI and high preoperative AHI. The perioperative lower SPO 2 (87.7 (74 - 94)) is decrease according to less upward movement of mandibular incisor.

Free Research Field

口腔顎顔面外科