• Search Research Projects
  • Search Researchers
  • How to Use
  1. Back to project page

2017 Fiscal Year Final Research Report

Control of rectal volume with Kampo formula during prostate radiotherapy: A prospective study

Research Project

  • PDF
Project/Area Number 15K14970
Research Category

Grant-in-Aid for Challenging Exploratory Research

Allocation TypeMulti-year Fund
Research Field Natural medicines
Research InstitutionTottori University

Principal Investigator

TAHARA TAKATOSHI  鳥取大学, 医学部附属病院, 講師 (30548772)

Project Period (FY) 2015-04-01 – 2018-03-31
KeywordsIMRT for prostate cancer / Rectal volume / Japanese herbal / Kampo
Outline of Final Research Achievements

During intensity-modulated radiation therapy (IMRT) for prostate cancer, volume and position of the rectum should be kept stable to minimize adverse events such as radiation proctitis or rectal bleeding. For this purpose, keeping the rectal volume small is essential. The purpose of this study was to investigate the effect of Daikenchuto (DKT), a traditional Japanese herbal (Kampo) on rectal volume during prostate IMRT prospectively. We divided total of 1,170 KV-CT of consecutive 30 non-metastatic prostate cancer patients into two groups. 15 patients were taken orally DKT (DKT group) and the others were not administered DKT (non-DKT group). Calculated rectal volumes of the DKT group were compared to those of the non-DKT group. Rectal volumes of DKT were smaller than that of non-DKT groups significantly. DKT appears to be useful in reducing rectal volume and intra-fractional volume variance which would help prevent radiation proctitis or rectal bleeding in prostate curative radiotherapy.

Free Research Field

放射線治療

URL: 

Published: 2019-03-29  

Information User Guide FAQ News Terms of Use Attribution of KAKENHI

Powered by NII kakenhi