2016 Fiscal Year Final Research Report
The role of B-cell expression in hepatic ischemia reperfusion injury
| Project/Area Number |
15K19857
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
General surgery
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| Research Institution | The University of Tokushima |
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Principal Investigator |
SAITO Yu 徳島大学, 大学院医歯薬学研究部(医学系), 助教 (50548675)
|
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| Project Period (FY) |
2015-04-01 – 2017-03-31
|
| Keywords | B細胞 / 肝虚血再灌流障害 |
|---|
| Outline of Final Research Achievements |
Liver ischemia-reperfusion (I/R) injury is one of critical problems to overcome in hepatectomy. Liver B cells among immune cells were focused on for the first time involved in I/R injury. Intrahepatic B cells might increase throughout CXCL13 / CXCR5 axis at relatively early time (2 hours) after reperfusion, and B cells can become therapeutic target in liver I/R injury.
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| Free Research Field |
医歯薬学
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