2016 Fiscal Year Final Research Report
Development of awake brain surgery for preservation of mentalizing
| Project/Area Number |
15K19957
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Neurosurgery
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| Research Institution | Kanazawa University |
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Principal Investigator |
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| Research Collaborator |
OKITA Hirokazu
NAKAJIMA Riho
INADA Yuna
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| Project Period (FY) |
2015-04-01 – 2017-03-31
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| Keywords | 心の理論 / 覚醒下脳手術 / トラクトグラフィ |
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| Outline of Final Research Achievements |
From the data of intraoperative mapping using theory of mind task in awake craniotomy for 15 right frontal gliomas, reproducible positive mappings could be confirmed in cortical and subcortical areas, and then overlapped on tractography and standardized brain MRI. A white matter tract "A" was a candidate tract subserving a network of mentalizing because of the three-dimensional distribution of positive mapping on the bundle in tractography and significant relationships between postoperative impairment of mentalizing and resected cavity including the white matter tract A in voxel-based lesion-symptom mapping analysis. This study suggested that structural preservation of white matte tract A would be able to maintain and improve mentalizing postoperatively in the resection of right frontal glioma.
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| Free Research Field |
脳神経外科
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