2007 Fiscal Year Final Research Report Summary
Metallomics of bio-trace elements : Copper, selenium and arsenic
| Project/Area Number |
16209004
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| Research Category |
Grant-in-Aid for Scientific Research (A)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Environmental pharmacy
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| Research Institution | Chiba University |
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Principal Investigator |
SUZUKI Kazuo Chiba University, Graduate School of Pharmacetical Sciences, Professor (90109918)
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| Co-Investigator(Kenkyū-buntansha) |
OGRA Yasumitsu Chiba University, Graduate School of Pharmacetical Sciences, Associate professor (40292677)
SUZUKI Noriyuki Chiba University, Graduate School of Pharmacetical Sciences, Research associate (10376379)
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| Project Period (FY) |
2004 – 2007
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| Keywords | environment / bio-trace elements / metallomics / arsenic / selenium / copper / ICP-MS |
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| Research Abstract |
Metallomics is a new scientific field in order to integrate the research fields related to biometals. Metallomics should be a scientific field in symbiosis with genomics and proteomics, because syntheses and metabolic functions of genes and proteins cannot be performed without the aid of various metal ions and metalloenzymes. In metallomics, metalloproteins, metalloenzymes and other metal- containing biomolecules are defined as metallomes, in a similar manner to genomes in genomics as well as proteomes in proteomics. Since the identification of metallomes and the elucidation of their biological or physiological functions in the biological systems is the main research target of metallomics, chemical speciation for specific identification of bioactive metallomes is one of the most important analytical technologies to establish metallomics as the integrated bio-metal science. In order to rationalize the concept of metallomics, the distributions of the elements in man, human blood serum and sea-water, a challenge to allelements analysis of one biological cell, and some other research topics are introduced with emphasis on recent development of chemical speciation of trace metals in some biological samples
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Research Products
(88 results)
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[Book] 生命元素事典2006
Author(s)
小椋康光
Total Pages
440
Publisher
オーム社
Description
「研究成果報告書概要(和文)」より
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