2006 Fiscal Year Final Research Report Summary
A population-based cohort study on serum vitamin-D in association with frailty among the community elderly
| Project/Area Number |
16390187
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| Research Category |
Grant-in-Aid for Scientific Research (B)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Public health/Health science
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| Research Institution | Tokyo Metropolitan Foundation for Research on Aging and Promotion of Human Welfare |
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Principal Investigator |
SUZUKI Takao Tokyo Metropolitan Foundation for Research on Aging and Promotion of Human Welfare, Tokyo Metropolitan Institute of Gerontology, Vice-Director, 東京都老人総合研究所, 副所長 (30154545)
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| Co-Investigator(Kenkyū-buntansha) |
YOSHIDA Hideyo Tokyo Metropolitan Foundation for Research on Aging and Promotion of Human Welfare, Tokyo Metropolitan Institute of Gerontology, Senior Research Scientist, 東京都老人総合研究所, 研究副部長 (00242735)
KIM Hunkyung Tokyo Metropolitan Foundation for Research on Aging and Promotion of Human Welfare, Tokyo Metropolitan Institute of Gerontology, Senior Research Scientist, 東京都老人総合研究所, 研究副部長 (20282345)
KWON Jinhee Tokyo Metropolitan Foundation for Research on Aging and Promotion of Human Welfare, Tokyo Metropolitan Institute of Gerontology, Research Scientist, 東京都老人総合研究所, 研究員 (50415494)
YOSHIDA Yuko Tokyo Metropolitan Foundation for Research on Aging and Promotion of Human Welfare, Tokyo Metropolitan Institute of Gerontology, Research Scientist, 東京都老人総合研究所, 研究員 (30321871)
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| Project Period (FY) |
2004 – 2006
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| Keywords | Serum vitamin D / Sarcopenia / Frailty / Functional capacity / Fall / Elderly |
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| Research Abstract |
Vitamin D deficiency characterized by low 25-hydroxy vitamin D [25 (OH) D] levels has been found to be prevalent among the elderly in many regions of the world. To investigate the vitamin D status in elderly community-living person in Japan, we measured 25 (OH) D at a baseline survey of 2004-2006.
As a result, we managed to measure 25 (OH) D of 4,305 elderly persons with age 65 and above living in communities. Major outcomes of the analysis on vitamin-D status are as follows: 1) Seasonal difference of 25 (OH) D ; measurement in summer is significantly higher level than in autumn. 2) Sex difference ; male at any age is significantly higher than female. 3) Institutionalized elderly showed significantly lower level of 25 (OH) D level than community/home-living elderly. And 4) lower level of 25 (OH) D is significantly associated with fall occurrence and decline of fall-related physical fitness.
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