2005 Fiscal Year Final Research Report Summary
Development of the optimal treatment schedule on high-dose-rate intracavitary brachytherapy for uterine cervical cancer
| Project/Area Number |
16591214
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Radiation science
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| Research Institution | University of the Ryukyus |
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Principal Investigator |
TOITA Takafumi University of the Ryukyus, Faculty of Medicine, Associate professor, 医学部, 助教授 (30237036)
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| Co-Investigator(Kenkyū-buntansha) |
KAKINOHARA Yasumasa University of the Ryukyus, Faculty of Medicine, Instructor, 医学部, 助手 (20185713)
KODAIRA Takeshi Aichi Cancer Center, Radiation Oncology, Chief, 医長 (80303626)
TESHIMA Teruki Osaka Univ., Medicine, Professor, 大学院・医学系研究科, 教授 (40136049)
MAEHAMA Toshiyuki University of the Ryukyus, Faculty of Medicine, Associate professor, 医学部, 助教授 (50157153)
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| Project Period (FY) |
2004 – 2005
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| Keywords | Uterine cervical cancer / Radiotherapy / High-dose-rate intracavitary therapy / multi-institutional cooperative study |
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| Research Abstract |
1)Multi-institutional prospective clinical study of definitive radiotherapy using high-dose-rate intracavitary brachytherapy for stage I, II uterine cervical cancer is ongoing. Patient entry started from September 24, 2004. Target sample size was calculated to be 60. The estimated accrual phase of the study is 3 years. Administrative office is placed in the Department of Radiation Oncology, National Cancer Center Hospital. The data is managed in the Department of Medical Physics and Engineering, Osaka University.
2)This study was approved by IRB in 16 institutions. At the time of this writing (April 25, 2006), 30 patients have been entered into the study.
3)To keep the quality of radiotherapy utilized in this study, quality assurance (QA) and quality control (QC) committee was organized. The QA/QC committee performed the first QA review of radiotherapy on 15 patients treated on February 4, 2006.
4)We will continue the patient entry, data management, and QA review on radiotherapy. After closing the patient entry, data will be analyzed and the results will be submitted to the international journals.
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