Analysis of generating factors on lumbar spondylolysis

2019 Fiscal Year Final Research Report

• Project/Area Number: 16K10825
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Multi-year Fund
• Section: 一般
• Research Field: Orthopaedic surgery
• Research Institution: The University of Tokushima
• Principal Investigator: SAKAI Toshinori 徳島大学, 大学院医歯薬学研究部(医学域), 准教授 (80403731)
• Co-Investigator(Kenkyū-buntansha): 西良 浩一 徳島大学, 大学院医歯薬学研究部(医学域), 教授 (10304528) ; 高田 洋一郎 徳島大学, 大学院医歯薬学研究部(医学域), 特任准教授 (20420549) ; 東野 恒作 徳島大学, 大学院医歯薬学研究部(医学域), 徳島大学専門研究員 (80380129) ; 手束 文威 徳島大学, 大学院医歯薬学研究部(医学域), 助教 (40782470)
• Project Period (FY): 2016-04-01 – 2020-03-31
• Keywords: 腰椎分離症 / 腰痛

Outline of Final Research Achievements

All the patients with terminal-stage spondylolysis had two separate arteries originating from the cranial and caudal sides that distributed to the superior and inferior articular processes, suggesting that the pars interarticularis is a posterior element containing a vascular watershed area. Extraosseous signal changes on MRI were detected in more than 90% patients before the occurrence of stress fracture in lamina (lumbar spondylolysis), which was considered similar to findings such as periosteal thickening/edema detected at the onset of stress fracture of the long bones. Although there are several limitations to this study, ESCs on MRI may be a significant finding accompanied with stress fracture in the lamina, which can be detected by ultrasonography.

Free Research Field

脊椎脊髄外科

Academic Significance and Societal Importance of the Research Achievements

腰椎分離症の病態解明につながる研究であり，また今後の腰椎分離症患者のスポーツ現場での早期発見また治療成績の向上につながるpreliminaryな結果と考えられる．