Embodiment of neuronal dissociate culture by reservoir computing

2016 Fiscal Year Final Research Report

• Project/Area Number: 16K14191
• Research Category: Grant-in-Aid for Challenging Exploratory Research
• Allocation Type: Multi-year Fund
• Research Field: Intelligent mechanics/Mechanical systems
• Research Institution: The University of Tokyo
• Principal Investigator: Takahashi Hirokazu 東京大学, 先端科学技術研究センター, 講師 (90361518)
• Project Period (FY): 2016-04-01 – 2017-03-31
• Keywords: 分散培養 / 脳

Outline of Final Research Achievements

This work investigated in primary dissociated cultures how neural circuits produce diversity of activity repertoire and how the static neural circuits produce stable, dynamic spatiotemporal patterns. In particular, considering a framework of reservoir computation, we characterized the neuronal circuits as a reservoir. We demonstrated that sequential propagation of neuronal sub-populations during synchronized activity underlies stability of neural representation. We also found a spontaneous, state-dependent property of neuronal activities, which is likely to play an important role to produce diversity of activity repertoire.

Free Research Field

神経工学