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2017 Fiscal Year Final Research Report

Studies on the pathological mechanisms of feline morbillivirus associated with chronic renal failure

Research Project

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Project/Area Number 16K15039
Research Category

Grant-in-Aid for Challenging Exploratory Research

Allocation TypeMulti-year Fund
Research Field Veterinary medical science
Research InstitutionKyoto University

Principal Investigator

Miyazawa Takayuki  京都大学, ウイルス・再生医科学研究所, 准教授 (80282705)

Research Collaborator SAKAGUCHI Shoichi  
KOIDE Rie  
TANIKAGA Takamasa  
IRIE Takashi  
FURUYA Tetsuya  
Mizutani Tetsuya  
Sindo Keiko  
Noda Takeshi  
Kuwahara Chieko  
Sakai Sachi  
Asai Ken-ichi  
Kawakami Kazuo  
Project Period (FY) 2016-04-01 – 2018-03-31
Keywordsネコモルビリウイルス / 猫 / 腎不全 / 免疫応答
Outline of Final Research Achievements

There have been few studies focusing on the relationships between cat nephritis and virus infections. However, feline morbillivirus (FeMV) associated with tubulointerstitial nephritis was discovered in Hong Kong in 2012. FeMV is classified as a member of Family Paramyxoviridae, Genus Morbillivirus, which is detected in urine and feces of FeMV-infected cats. Since FeMV was detected in cats in various Asian, European and American countries, it is considered that the virus is prevalent all over the world. On the other hand, the pathobiological mechanisms of this virus is still unknown. Therefore, in this study, we focused on the immune responses of the hosts in FeMV-infected cats and studied the relationships between FeMV infection and viral nephritis in cats.

Free Research Field

獣医ウイルス学

URL: 

Published: 2019-03-29  

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