2017 Fiscal Year Final Research Report
Combined effects of components of PM2.5 on early stage of biological and immune responses.
| Project/Area Number |
16K19272
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Hygiene and public health
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| Research Institution | Kyoto University |
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Principal Investigator |
Honda Akiko 京都大学, 工学研究科, 助教 (20454324)
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| Project Period (FY) |
2016-04-01 – 2018-03-31
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| Keywords | PM2.5 / アレルギー / 気管支喘息 / 複合影響 |
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| Outline of Final Research Achievements |
We investigated combined effects of components of PM2.5 on respiratory and immune cells to elucidate the underlying mechanisms by which PM2.5 lead to the development and/or exacerbation of allergic diseases such as asthma. This study indicates components of PM2.5 can contribute to the development and/or exacerbation of asthma by disruption of respiratory and immune systems independently or synergistically.
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| Free Research Field |
環境毒性学
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